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Báo cáo khoa học: An orphan dermaseptin from frog skin reversibly assembles to amyloid-like aggregates in a pH-dependent fashion pptx

Báo cáo khoa học: An orphan dermaseptin from frog skin reversibly assembles to amyloid-like aggregates in a pH-dependent fashion pptx

Báo cáo khoa học: An orphan dermaseptin from frog skin reversibly assembles to amyloid-like aggregates in a pH-dependent fashion pptx

... Gharibyan AL, Zamotin V, Yanamandra K, MoskalevaOS, Margulis BA, Kostanyan IA & Morozova-RocheLA (2007) Lysozyme amyloid oligomers and fibrilsinduce cellular death via different apoptotic ... out a cytolyticmechanism. In some instances, antimicrobial peptides such asapidaecin [28] are directed against intracellular targetsrather than against the cell membrane. However,protofibrils, ... appear during apoptosis andaccompany protofibril action. Therefore, our resultsindicate that aDrs aggregates act via an independent,as yet unidentified mechanism. In contrast to protofibrils, amyloid...
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Tài liệu Báo cáo khoa học: An alternative transcript from the death-associated protein kinase 1 locus encoding a small protein selectively mediates membrane blebbing pdf

Tài liệu Báo cáo khoa học: An alternative transcript from the death-associated protein kinase 1 locus encoding a small protein selectively mediates membrane blebbing pdf

... protein kinase 1 (DAPK-1) is a Ca2+⁄ calmodulin-regulated serine ⁄ threonine kinasecomposed of multiple functional domains, including a kinase domain, a calmodulin-binding domain, eightankyrin ... ofDAPK-1’s ankyrin-repeat region, P-loop, and cytoskel-etal binding domain, and a unique tail of 42 aminoacids encoded by intron 20–21 of the DAPK-1 gene. In our examination of DAPK-1 and s-DAPK-1 ... 2008)doi:10.1111/j.1742-4658.2008.06404.xDeath-associated protein kinase 1 (DAPK-1) is a multidomain proteinkinase with diverse roles in autophagic, apoptotic and survival pathways.Bioinformatic screens were used to identify a small...
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Báo cáo khoa học:

Báo cáo khoa học: "AN APPLICATION OF AUTOfIATED LANGUAGE UNDERSTANDI;IG TECHNIQUES TO THE GENERATION OF DATA BASE ELEMENTS" potx

... AN APPLICATION OF AUTOfIATED LANGUAGE UNDERSTANDI;IG TECHNIQUES TO THF GENERATION OF DATA BASE ELEMENTS Georgette Silva, Christine Montoomerv. and Don Dwiggins Operating Systems, Inc. ... traffic in a military environment. The approach taken leans heavily on theoretical ad-' vances in several disciplines, including linguistics, computational linguistics, artificial intelligence, ... SUBLANGUAGE The two sublanguage domains studied thus far consist of descriptions of events involving aircraft activities and launchings of missiles and satel]ites. The source data are contained...
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Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx

Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx

... ⁄ Abl and ⁄ or phosphoinositide-3-kinase mayalso activate the small Rho GTPases Cdc42 and Rac1,and binding of CagAPY to Grb2, or Shp2 may regulateproliferative and pro -in ammatory signalling ... pylori to enter the intercellular space between adjacent cells and reach the basal membranes (11). In this manner, the bacteria could access integrins and inject CagA (12). Injected CagA can then induce ... ofbacteria gain access to integrins and inject CagA. Thebasal injection model of CagA can also explain whyH. pylori does not cause more gastric damage in infected individuals and may only inject...
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Tài liệu Báo cáo khoa học: Abstract Integration of Metabolism and Survival PP-1 The metabolic switch in liver methionine metabolism pptx

Tài liệu Báo cáo khoa học: Abstract Integration of Metabolism and Survival PP-1 The metabolic switch in liver methionine metabolism pptx

... antioxidant stobadine has been demonstrated to repairoxidized amino acids and to preserve oxidation of SH groups.Taurine, an endogenous antioxidant and a membrane stabilizingamino acid, may ... Acute in ammation reducesthe L-arginine/ADMA ratio, which could contribute to in amma-tory injury. Taurine may offer an advantage in because of itincrease the reduced L-arginine/ADMA ratio. ... various in am-matory injuries. Asymmetrical dimethylarginine (ADMA) is theendogenous NOS inhibitor. Taurine is an abundant free aminoacid in inflammatory cells that protects cells from in ammatorydamages....
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Báo cáo khoa học:

Báo cáo khoa học: "Combining POMDPs trained with User Simulations and Rule-based Dialogue Management in a Spoken Dialogue System" docx

... uniform way. This facilitates dialog eval-uation, data mining and online learning becausedata is available for querying as soon as it hasbeen stored. There is no need for separate loggingmechanisms. ... DM, to ob-tain training data from human-system interactionfor the user simulator, and to understand the prop-erties of the domain (Varges et al., 2008). Rule-based dialog management works in ... rule-based and trainable dialoguemanagers, spoken language understandingand generation modules, and a compre-hensive dialogue system architecture. Wepresent a Reinforcement Learning-baseddialogue...
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Báo cáo khoa học: Structure of the O-polysaccharide fromProteus myxofaciens Classification of the bacterium into a newProteusO-serogroup pptx

Báo cáo khoa học: Structure of the O-polysaccharide fromProteus myxofaciens Classification of the bacterium into a newProteusO-serogroup pptx

... gel-per-meation chromatography on Sephadex G-50. Analysis ofthe polysaccharide using an amino-acid analyzer revealedthe presence of GlcN and GalN in the ratio 2 : 1 as well asanother amino component. ... penneri and P. hauseri,aswellas three unnamed Proteus genomospecies 4, 5 and 6 [1,2].They are widely distributed in nature and are importantfacultative human and animal pathogens, which in favorable ... spectra were obtained usingstandard Bruker software, and theXWINNMR2.1 program(Bruker) was used to acquire and process the NMR data. A mixing time of 200 and 300 ms was used in TOCSYand ROESY...
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Báo cáo khoa học:

Báo cáo khoa học: "Adaptation of Statistical Machine Translation Model for Cross-Lingual Information Retrieval in a Service Context" ppt

... evaluation of machinetranslation.Pavel Pecina, Antonio Toral, Andy Way, Vassilis Pa-pavassiliou, Prokopis Prokopidis, and Maria Gi-agkou. 2011. Towards using web-crawled data fordomain adaptation ... 29(1):19–51.Franz Josef Och, Daniel Gildea, Sanjeev Khudanpur,Anoop Sarkar, Kenji Yamada, Alex Fraser, ShankarKumar, Libin Shen, David Smith, Katherine Eng,Viren Jain, Zhen Jin, and Dragomir Radev. ... Fujii, Masao Utiyama, Mikio Yamamoto, andTakehito Utsuro. 2009. Evaluating effects of ma-chine translation accuracy on cross-lingual patentretrieval. In Proceedings of the 32nd internationalACM...
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Tài liệu Báo cáo khoa học: An investigation of the substrate specificity of the xyloglucanase Cel74A from Hypocrea jecorina pdf

Tài liệu Báo cáo khoa học: An investigation of the substrate specificity of the xyloglucanase Cel74A from Hypocrea jecorina pdf

... and Avicel were obtained from Sigma-Aldrich, and the cello-oligosaccharides were obtained from Merck (Darmstadt, Germany). The oligosaccharidesderived from b-glucan were a gift from A Planas ... matureprotein (SwissProt Q7Z9M8), consisting of a catalyticdomain, a linker region, and a C-terminal carbohy-drate-binding module. A high apparent molecular massfor intact Cel7 4A (105 kDa) was also ... xyloglucanasesare discussed.Results and DiscussionProtein characterizationCel7 4A was purified to apparent homogeneity from an engineered strain of H. jecorina by a combination ofgel filtration and...
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Tài liệu Báo cáo khoa học: The SCO2299 gene from Streptomyces coelicolor A3(2) encodes a bifunctional enzyme consisting of an RNase H domain and an acid phosphatase domain pdf

Tài liệu Báo cáo khoa học: The SCO2299 gene from Streptomyces coelicolor A3(2) encodes a bifunctional enzyme consisting of an RNase H domain and an acid phosphatase domain pdf

... enzyme consisting of an RNase Hdomain and an acid phosphatase domainNaoto Ohtani1, Natsumi Saito1, Masaru Tomita1, Mitsuhiro Itaya1,2and Aya Itoh11 Institute for Advanced Biosciences, ... 88,12–19.19 Ohtani N, Yanagawa H, Tomita M & Itaya M (2004)Identification of the first archaeal type 1 RNase H gene from Halobacterium sp. NRC-1: archaeal RNase HI cancleave an RNA-DNA junction. ... Tsuruoka, Yamagata, Japan2 Mitsubishi Kagaku Institute of Life Sciences, Machida, Tokyo, JapanIt is generally accepted that ribonuclease H (RNaseH; EC 3.1.26.4) specifically cleaves an RNA strandof...
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