Báo cáo khoa học: The effect of zinc oxide nanoparticles on the structure of the periplasmic domain of the Vibrio cholerae ToxR protein pot

Báo cáo khoa học: The effect of zinc oxide nanoparticles on the structure of the periplasmic domain of the Vibrio cholerae ToxR protein pot

Báo cáo khoa học: The effect of zinc oxide nanoparticles on the structure of the periplasmic domain of the Vibrio cholerae ToxR protein pot

... Authors Journal compilation ª 2010 FEBS The effect of zinc oxide nanoparticles on the structure of the periplasmic domain of the Vibrio cholerae ToxR protein Tanaya Chatterjee 1 , Soumyananda ... work we report the unfolding behavior of the periplasmic domain of the ToxR protein (ToxRp) of Vibrio cholerae on zinc oxide (ZnO)...
Ngày tải lên : 23/03/2014, 03:20
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Báo cáo khoa học: A new rice zinc-finger protein binds to the O2S box of the a-amylase gene promoter pptx

Báo cáo khoa học: A new rice zinc-finger protein binds to the O2S box of the a-amylase gene promoter pptx

... whether the expression of the RAMY gene is induced by GA, and the possible relationship between the expression of the RAMY gene and the Amy2 gene, we performed a Northern blot hybridization e ... binding domain is present in the protein. This conclusion is supported by the observations that the RAMY Fig. 5. DNA binding is mediated by the zinc finger domain. (A) SD...
Ngày tải lên : 16/03/2014, 18:20
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Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx

Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx

... regulation of the three thyroid cell lines We investigated the effects of XCT790, a specific inverse agonist of ERRa. As controls of the inhibitory effect of XCT790 on ERRa, we used the expression of ERRa-validated ... vehicle. On the sixth day, the cells were transfected with control or PRC siRNA. (A) Oxygen consumption defined in the basal condition (basal resp...
Ngày tải lên : 06/03/2014, 09:22
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Báo cáo khoa học: Retrocyclin RC-101 overcomes cationic mutations on the heptad repeat 2 region of HIV-1 gp41 ppt

Báo cáo khoa học: Retrocyclin RC-101 overcomes cationic mutations on the heptad repeat 2 region of HIV-1 gp41 ppt

... regions of gp41 [12]. During 100 days of serial passaging, HIV-1 strain BaL developed three cationic mutations in the presence of sublethal concentrations of RC-101 [14]. Of the three mutations, ... thus the dependence of viral replication on the presence of RC-101 is not surprising. The cationic mutations and loss of glycosylated residues suggest an attempt by th...
Ngày tải lên : 07/03/2014, 05:20
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Báo cáo khoa học: Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats ppt

Báo cáo khoa học: Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats ppt

... not obligatory, to the atherogenic process. The important corollary is that inhibition of such oxidation should reduce the progression of atherosclerosis, independent of reduction of other factors, ... alteration in endothelial function, are considered among the early events in the pathogenesis of atherosclerosis [43]. The alteration of oxidant ⁄ antioxidant balance ma...
Ngày tải lên : 08/03/2014, 08:20
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Báo cáo khoa học: What’s in a covalent bond? On the role and formation of covalently bound flavin cofactors doc

Báo cáo khoa học: What’s in a covalent bond? On the role and formation of covalently bound flavin cofactors doc

... observed on mutating the amino acids involved in covalent flaviny- lation. As mentioned before, removal of one of the covalent bonds affects the redox potential. However, on the basis of changes in the ... compari- son of structure of the flavoprotein harboring covalently bound FAD [39] with the structures of the flavoprotein with noncovalently bound FAD or the...
Ngày tải lên : 16/03/2014, 01:20
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Báo cáo khoa học: Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions docx

Báo cáo khoa học: Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions docx

... enhance Sp1 activity in these conditions. This effect was no longer observed at higher concentrations. The protein level of Sp1 was checked in the different conditions: the results showed that ... result of the loss of the molecule during the extraction procedure: indeed, only the nuclear proteins are recovered and the DNA is dis- carded. By contrast, when echinomyci...
Ngày tải lên : 16/03/2014, 05:20
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Báo cáo khoa học: Protective effect of active oxygen scavengers on protein degradation and photochemical function in photosystem I submembrane fractions during light stress pdf

Báo cáo khoa học: Protective effect of active oxygen scavengers on protein degradation and photochemical function in photosystem I submembrane fractions during light stress pdf

... scavengers used that only the generation of 1 O 2 is responsible for the photooxidation effects. The role of active oxygen scavengers in the protection of the structure and function of the photo- systems ... The main site of PSI photo- inhibition under aerobic conditions was then shown to be the inactivation of iron–sulfur centers [11], whereas anaerobic photoinh...
Ngày tải lên : 16/03/2014, 18:20
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Báo cáo khoa học: A guide to taming a toxin – recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer ppt

Báo cáo khoa học: A guide to taming a toxin – recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer ppt

... native PE. Functionally, domain I of PE is the receptor-binding domain, and is the major component of the B subunit. Cancer therapy based on Pseudomonas exotoxin A J. E. Weldon and I. Pastan 4684 ... dependent on the degradation of Mcl-1 and release of Bak [123]. The anti-apoptotic protein Mcl-1 is rapidly turned over in the cell, and inhibition of its synthesis...
Ngày tải lên : 22/03/2014, 15:21
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Báo cáo khoa học: Catalytic residues Lys197 and Arg199 ofBacillus subtilis phosphoribosyl diphosphate synthase Alanine-scanning mutagenesis of the flexible catalytic loop ppt

Báo cáo khoa học: Catalytic residues Lys197 and Arg199 ofBacillus subtilis phosphoribosyl diphosphate synthase Alanine-scanning mutagenesis of the flexible catalytic loop ppt

... 3631 acids of the loop, Lys197 and Arg199 are highly con- served, whereas the remaining 10 amino acids are only moderately conserved. Crystallization of the enzyme in the presence of the transition state ... [19–21]. The conformation of the flag region, of which the flexible loop is a part, varies con- siderably; the loop is either completely unresolved or in a very...
Ngày tải lên : 23/03/2014, 15:20
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