... Venkatesh1,21Department of Chemical Engineering and2School of Biosciences and Bioengineering, Indian Institute of Technology Bombay,Powai, Mumbai, IndiaCellular regulation is a result of complex interactions ... interactions, thus raising questions regard-ing prevalent in v ivo mechanisms. Performance of theCorrespondence to K. V. Venkatesh, Department of ChemicalEngineering, Indian Institute of Technology, ... complex interactions arisingfrom DNA–protein and protein–protein binding, autoreg-ulation, and c ompartmentalization and shuttling o f regula-tory proteins. Experiments in molecular biology haveidentified...