... Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21dependent but p53 independent. Cancer Res 64,7412–7419.65 O’Sullivan J, Whyte L, Drake J & Tenniswood M(2003) ... apoptosis of HaCaT cells is mediated byc-fos and involves nuclear accumulation of clusterinSoultana Markopoulou1,*, Evangelos Kontargiris1,*, Christina Batsi1,*, Theodore Tzavaras2,Ioannis ... Japan) fitted with a camera(Nikon cool pix 990; Nikon Corp., Tokyo, Japan).DNA fragmentation assayDNA fragmentation analysis of VOSO4-treated anduntreated cells was performed as described previously[29,30]....