Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... DNA supercoiling in
Escherichia coli
is under tight and subtle
homeostatic control, involving gene-expression and metabolic
regulation of both topoisomerase I and DNA gyrase
Jacky L. Snoep
1,2
, ... on
supercoiling:
C
supercoiling
gyrase
1
e
v
topoisomerase I
supercoiling
e
kt
topoisomerase I
supercoilin g
Àe
v
gyrase
super...
... complexes. EII is typically composed
of EIIA, B and C domains, with the EIIA and B do-
mains being part of the phosphorylation chain and the
EIIC domain representing the membrane domain. As
all ... this study, we compare two models describing
catabolite repression in E. coli by discussing some
relevant issues of modelling in systems biology, model
validation, dynamics and...
... Refolding of the
Escherichia coli
expressed extracellular domain
of a7 nicotinic acetylcholine receptor
Cys116 mutation diminishes aggregation and stabilizes the b structure
Victor I. Tsetlin
1
, ... denatured
proteins and therefore is widely used in refolding studies
[28–30]. It is assumed that the masking of hydrophobic
protein interfaces by detergent molecules results...
... presence of some tertiary contacts involving at
least one of the tyrosines, although the intensity of
each peak is not very high.
To gain further insight into the conformational prop-
erties of EspB, ... amino acid residues at 1–53, 128–230 and 247–287
may be disordered. This is relatively consistent with the
prediction of DisEMBL. If the prediction from
PONDR is correct,...
... presented in this study indicates that the center had achieved its primary
tasks. Such regional organization with executive, planning, teaching and training responsibilities
offers possibilities for ... shipping
and public gatherings all need to be included in the risk
assessment regarding possible major incidents in this
region. The purpose of this study was to find whether this...
... urinary acidification defects [42].
Patients with preexisting kidney disease are at increased
risk for lithium toxicity and possibly the nephrotoxic
effects of lithium. Lithium is contraindicated in ... plasma
proteins, thereby increasing free-drug levels; increase in
volume of distribution in patients with ascites [52].
Hepatitis C virus (HCV) infection is a leading cause of...
... efficacy of
decompressive craniectomy in decreasing ICP and
improving pr o g n o sis in patients wi th refractory in-
tracranial hypertension after TBI.
2-8
Presently, th e
European Brain Injury ... that maintains the blood supply.
Brain herniation via the craniectomy defect may
lead to compression of vessels and result in ischemic
necrosis of the portion of the her...
...
http://www.medsci.org
237
Microbiologic procedures in joint infections
A differentiation of arthritis is practicable by
examination of typical laboratory medicine and mi-
crobiology characteristics in joint ...
Abstract
Infections of the hip joint are usually of bacterial etiology. Only rarely, an infectious arthritis
is caused in this localization by viruses or fung...
... heterozygosity and tighter linkage
disequilibrium with disease-causing mutations. In ad-
dition, haplotype analysis offers the advantage of not
assuming that any of the genotyped polymorphisms is ... Because this polymorphism is located in the
vicinity of the translation initiation codon, it may alter
translation efficiency. The nearby proximal nucleo-
tides to the AUG ini...
... methodology of in vitro prion propagation assays and discuss their ability in reflecting prion propaga-
tion in vivo.
Key words: prion disease, prion, cellular prion protein, disease-associated scrapie ...
transmit disease directly to wild type mice. To obtain
infectivity in wild type mice, synthetic prions were
Int. J. Med. Sci. 2008, 5
352
serially passaged to wild type m...