... stress (Eur. J. Biochem. 269) 3085
Cellular stresses profoundly inhibit protein synthesis and modulate
the states of phosphorylation of multiple translation factors
Jashmin Patel
1
, Laura E. ... study the
roles of stress-activated signalling pathways on cell func-
tion. We find that these stresses rapidly and profoundly
inhibit protein synthesis...
... University of Adelaide, South Australia
Two neuropeptides have been isolated and identi®ed from
the secretions of the skin glands of the Stony Creek Frog
Litoria l esueuri. The ®rst of these, the ... Ca
2+
calmodulin,
the inhibition dropped by 50% in each case. In addition,
these peptides also inhibit the activity of calcineurin, another
enzyme that requires the...
... in the plasma membrane of
dormant granulocytes in spite of the fact that they were
observed abundantly in cytoplasm. Whereas reactive
oxygen species are classically thought of as cytotoxic and
mutagenic ... from the column were pooled and
employed to detect PAK and Rac by Western blot. Protein
was quantitated by the method of Bradford [25], using BSA.
Immunoprecipitati...
... designed the study, collected the data, performed the statistical
analysis and drafted the manuscript. HML and ES helped design the study
and draft and review the manuscript. All authors have read and ... Norway.
2
Department of Anaesthesiology and Intensive
Care, Stavanger University Hospital, Stavanger, Norway.
3
Department of
Surgical Sciences, Faculty of medi...
... satisfaction with the
duration of effect of the study medication on their child's
ADHD symptoms.
Regarding medication satisfaction with tolerability of
MTS, at study endpoint the majority of caregivers ... that the study medication decreased their child's
appetite. The majority of caregivers (88.1%) disagreed
that the study medication made their child feel slee...
...
therapy. We investigated the safety and effectiveness of oral rehydration therapy (ORT) for
preoperative fluid and electrolyte management of surgical patients.
Methods: The study consisted of ... of ORT for the
preoperative fluid and electrolyte management of
patients receiving general anesthesia before breast
surgery, and in the follow-up study on the safety...
... to dissect the cyst with
minimal injury to the peripheral tissue, the cystic liq-
uid was partly withdrawn first and the slackened cyst
was removed totally. The liquid was yellowish and
transparent. ... and the spinal cord was found swollen. When a
midline myelotomy was performed, a white cystic
lesion was seen and clear fluid was then aspirated.
The cyst wall of...
... (CagA)
protein a nd vacuolating cytotoxin (VacA) protein are
the main virulence factors of Hp and closely relevant
with the occurrence of gastric ulcer and carcinoma [2].
Most H. pylori strains ... mutations was de-
pendent on the bacterial virulence factors. The
changes in mtDNA in peptic ulcer tissues may further
impair the ATP synthesis and increase the m...
... on the far
wall of the common carotid artery along a 1 cm sec-
tion of the artery proximal to the carotid bulb. The
IMT was defined as the distance between the inti-
mia-blood interface and the ... (Modula Analytics PP, Roche). Both
intra-assay and inter-assay coefficient of variations
were less than 2.1% and 4.4%, respectively. Plasma
levels of IL-6 and T...
... utilizes the synthetic tri-
peptide substrate N-[3-(2-furyl)acryloyl]
phenylalanylglcylglcine (FAPGG). FAPGG is hydro-
lyzed by ACE to furylacryloylphenylalanine (FAP)
and glycylglycine. Hydrolysis ... and throughout the re-
mainder of the study.
The entire BP profile and heart rate were as-
sessed near the end of the study as shown in Table 3.
Measured by another meth...