Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... 2002 Ku proteins regulate transcription of the WD gene (Eur. J. Biochem. 269) 2161 Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens ... presence of nuclear factors that bind specifically to MREa. Two MREa-binding proteins of 70 and 82 kDa were purified using avidin–biotin a nity chromatography. Amino acid sequences of peptidesfrom each ... indicate the two MREa-binding proteins are closelyrelated or identical to the Ku proteins. The effects of RNAi of the Ku- 80 subunit and the truncated Ku- 80 mutant on WD gene expression To examine...
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Báo cáo y học: "Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients
... effects and minimize toxicities [16-19]. Since digoxin is mainly eliminated via the kidneys, the renal function of the patients and its alteration during therapy are important factors to conduct ... concluded that Cys-C is a more useful marker for GFR than Cr [5]. A multinational expert meeting was held in Germany to summarize the latest findings also in 2002, and it was finally concluded that ... Turbidimetric Inhibition ImmunoAssay (PETINIA) with a Dimension Xpand-HM (Dade Behring LIMITED). The results were routinely validated to confirm acceptable precision and accuracy. Statistical analysis...
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Báo cáo y học: "Autofluorescent Proteins as Photosensitizer in Eukaryonte"
... death in yeast and in saccharomyces cerevisiae is documented16,17. In com-parison, in case of radical or reactive oxygen forma-tion, the amount of data investigations about pro-karyotes and ... interest on pharmacologically inactive molecules which are converted after activation by daylight to photosensitizing agents and which are able to dam-age, mutate and finally kill eukaryotic cells. ... mutation and finally killing of eukaryotic cells. We found evidence that the KRED’s cytotoxicity is ascendantly location-dependent from the cell membrane over the nuclear lamina to the chromatin...
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Báo cáo Y học: Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells pptx
... receptors.All-trans-RA inhibits the DNA binding activity of NFAT To understand the molecular m echanism of RA-inducedinhibition of NFAT activity, we investigated whether the DNA-binding activity ... homeostasis of lymphocytes, and the main-tenance of peripheral tolerance. Retinoids, vitamin A and itsnatural and synthetic derivatives, regulate a wide array of biological processes, includin ... T-cells(NFAT), which is an important transactivator of the FasL promoter. The analysis of reporter constructs containing the FasL promoter and wild-type or mutant NFAT binding-sites indicated that all-trans-RA...
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Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... oxygenase and reductase domains is determined by the regulatory enzyme calmodulin that interacts a t a speci®c site between the t wo domains. In the cases of the nNOS and e NOS isoforms, the calmodulin ... catalytic oxygenasedomain t hat binds heme, tetrahydrobiopterin and the substrate arginine, and (b) the electron-supplying reductasedomain that binds NADPH, FAD a nd FMN. Communi-cation between the ... amphibian peptides are affecting the Ca2+calmodulin interaction with nNOS. This is an interesting observation because sequences of the Ca2+calmodulin binding sites of nNOS and calcineurin are quite...
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Báo cáo Y học: Nuclear receptor-dependent transcription with chromatin Is it all about enzymes? pot
... role for histone acetylation, namely to create binding sites on the amino-terminal tails of core histones for acetylated lysinebinding domains, such as the bromodomain (reviewed in [91]), similar ... to the way that methylated H3-K9 serves as a binding site for chromodomain-containing proteins (des-cribed above). A mechanism like this may allow for the recruitment of bromodomain-containing ... well-established, yet the exactmechanism of how histone acetylation leads to enhancedactivation is not clear. Although histone acetylation wasoriginally thought to facilitate chromatin remodeling...
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Báo cáo Y học: Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system docx
... 5¢-GAATTCATGCATCCCTTCTACACC-3¢(TobF)5¢-GTCGACTTAGTTAGCCATAACAGGC-3¢(TobR)(59–345) 5¢-GAATTCCACATAGGGGAGAAAGTG-3¢ TobR(84–345) 5¢-GAATTCGGCAATCTGCCACAGGAT-3¢ TobR(114–345) 5¢-GAATTCGTGGATGATAATAATGAA-3¢ TobR(1–315) TobF 5¢-GTCGACTTAGCCTCCATAGGCTGC-3¢(1–277) ... 5¢-GTCGACTTAGCCTCCATAGGCTGC-3¢(1–277) TobF 5¢-GTCGACTTAAGGAAAAATAAATTCCTT-3¢GFP–Tob (285–345) 5¢-GAATTCACCAATGGAATGTTCCCA-3¢ TobRTob2 (full length) 5¢-GAATTCATGCAGCTAGAGATCAAAGT-3¢(Tob2F)5¢-GTCGACTCAGTTGGCCAGCACCA-3¢(Tob2R)(59–344) ... family proteins, it is possible that phosphorylation is a signal for this degradation, because ithas been reported that Tob is phosphorylated by a Tob-associating kinase [41] and that cyclin-dependent...
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Báo cáo y học: "Using Medical Emergency Teams to detect preventable adverse events"
... criticalcare nurse, and a critical care-trained respiratory therapist. The MET can be activated by any hospital staff and is active 24hours a day. Providers in our hospital use standard criteria ... calls. Within a week of the MET call, a multi-disciplinary team reviewed the information and rated the cause of the outcome using a previously developed rating scale. Weclassified the type and ... is a 487-bed tertiary care teaching hospital. It implemented an MET in January 2005. The team is composed of a physician (intensiv-ist during the day and a critical care resident at night), a...
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Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... pharmacologically active form of pravas-tatin is open hydroxyl-acid so that its hydrophilicity is markedly higher than that of other statins. The oral bioavailability of this statin is low due to degradation ... so that they are used in the treat-ment of many diseases such as osteoporosis, Alz-heimer disease, organ transplantation, stroke and di-abetes [1]. Administration of statins by oral rout is ... Loaded amount The total amount of pravastatin entrapped in 0.1 ml of the final packed erythrocytes. Efficiency of entrapment The percentage of the loaded amount of pravas-tatin to the total...
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Báo cáo y học: "Current Status of Methods to Assess Cancer Drug Resistance"
... risk. The main aim is creating validated biomarkers for early thera-peutic intervention in malignant diseases [47, 48]. A large number of organizations are now participating in cancer biomarker ... cellu-lar signal transductors and thus act mainly cytostati-cally compared with classical cytotoxic drugs require special timing of scans [68]. International guidelines for PET tests are therefore ... intrinsic drug re-sistance in the individual patient. However, there may be some difficulty to find a specialized laboratory that can carry out the laborious and error-prone assays and can...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămbáo cáo y tế học đường năm 2012báo cáo y tế học đường trường mầm nonbiểu mẫu báo cáo y tế trường họcbáo cáo y tế học đường trường tiểu họcbáo cáo y tế trường tiểu họcbáo cáo y tế trường học năm 2012Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngChuong 2 nhận dạng rui roBT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật