Báo cáo khoa học: "Learning How to Conjugate the Romanian Ve

Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modiﬁcations ppt

... instances [18]. The limited availability of singu- lar glycoforms has prompted a concerted effort to develop new methods for their synthesis [8]. Biological methods to obtain glyco- proteins The natural ... [33], the ﬁrst reported modular total synthesis of a biologically rele- vant glycoprotein. The immediate compatibility of NCL and EPL methods has led to their widespread...

Ngày tải lên : 18/02/2014, 17:20

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Tài liệu Báo cáo khoa học: From heart to mind The urotensin II system and its evolving neurophysiological role ppt

... particularly with regard to arousal and sleep. Molecular constituents of the UII system Presently, three molecules are known to form the UII system: the UII receptor and the peptides UII and urotensin-related ... reported the identiﬁca- tion of the UII receptor, an orphan receptor known before as both GPR14 or SENR (for sensory epithe- lium neuropeptides-like receptor...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Comparative studies of endonuclease I from cold-adapted Vibrio salmonicida and mesophilic Vibrio cholerae docx

... seems to have on the RNase activity of the enzymes may be linked to an increase in Na + around the phosphate groups and the 2¢-OH, which reduces the negative charge, and hence the afﬁnity of the enzyme ... for an in-line attack on the scissile phosphate in the DNA substrate. The role of the active-site magnesium ion is to stabilize the phosphoanion transiti...

Ngày tải lên : 19/02/2014, 05:20

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Báo cáo khoa học: cAMP response element-binding protein (CREB) is imported into mitochondria and promotes protein synthesis docx

... the antioxidant iron che- lator deferoxamine of PKA, localized in the mitochondrial matrix [21], promoted CREB binding to the mtDNA D-loop. The presence in mitochondria of the CREB factor and, ... in the expression of mitochondrially encoded proteins of the respiratory chain prompted us to investigate the mitochondrial import of the CREB protein, synthesized in vitro,...

Ngày tải lên : 07/03/2014, 02:20

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Báo cáo khoa học: Unusual stability of human neuroglobin at low pH – molecular mechanisms and biological signiﬁcance docx

... exogenous ligands, both the ferrous and ferric forms of Ngb are hexacoordinated, with the proximal His64 being the endogenous ligand. Therefore, Ngb ligand binding requires the displacement of the intramolecular ... taken from the reaction mixture, and the proteolysis was stopped by adding to the mixture the inhibitor pepstatin (enzyme ⁄ inhibitor molar ratio of 1 : 5)...

Ngày tải lên : 07/03/2014, 02:20

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Báo cáo khoa học: Nitric oxide formation from the reaction of nitrite with carp and rabbit hemoglobin at intermediate oxygen saturations pdf

... and equilibrated for 1 h in the shaking tonometer to ensure full equilibration of the Hb to the gas atmosphere of the system. The tonometer was then transferred to a Cecil CE2041 spec- trophotometer (Cambridge, ... 2008 The Author Journal compilation ª 2008 FEBS 3381 The addition of ATP to stabilize the T state and to impede the T to R transition caused th...

Ngày tải lên : 16/03/2014, 06:20

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Báo cáo khoa học: R120G aB-crystallin promotes the unfolding of reduced a-lactalbumin and is inherently unstable ppt

... the period of a week, the 1 H-NMR spectrum of R120G aB-crystallin was monitored. Figure 3 shows the aromatic and NH region of the 1D 1 H-NMR spectrum and the NH to a,b,c-CH region of the 2D TOCSY ... and pH 7.0. (A) 1D spectra of the aromatic and NH region; (B) cross-peaks from the NH to a,b,c-CH protons in TOCSY spectra. The increasing complexity of the spectr...

Ngày tải lên : 16/03/2014, 18:20

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Tài liệu Báo cáo khoa học: "Learning to Translate with Multiple Objectives" doc

... instance the pareto- optimal point (0.4,0.7). There is no other point with either (metric1 > 0.4 and metric2 ≥ 0.7), or (met- ric1 ≥ 0.4 and metric2 > 0.7). On the other hand, the non-pareto ... of pareto-optimal points. A hypothesis is weakly pareto-optimal if there is no other hypothesis that improves all the metrics; a hypothesis is pareto- optimal if there is no other hy...

Ngày tải lên : 19/02/2014, 19:20

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Tài liệu Báo cáo khoa học: "Learning to Find Translations and Transliterations on the Web" doc

... engine, and automatically annotating the snippets with tags and features for training a conditional random field model. At run- time, the model is used to extracting translation candidates for ... translations for a given phrase. The system begins by submitting the given phrase as query to a search engine to retrieve snippets, and generate features for each t...

Ngày tải lên : 19/02/2014, 19:20

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Tài liệu Báo cáo khoa học: "Learning to Follow Navigational Directions" pdf

... allocentric (landmark-centered) features. For example, the top left ﬁgure shows that when the word above occurs, our policy prefers to go to the north of the target landmark. The bottom row shows the weights ... respect to two metrics: the order in which we visit landmarks and the side we pass them on. To determine the order P e visits landmarks we compute the...

Ngày tải lên : 20/02/2014, 04:20

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Báo cáo khoa học: "Learning How to Conjugate the Romanian Verb Rules for Regular and Partially Irregular Verbs" docx