... ele-
ments, very little is known about their role in DIDO
activity.
The combination of domains (domain shuffling)
is a driving force in Eukarya in the acquisition of
Keywords
CGBP; DATF1; DIDO1; DIO; ... from the other bran-
ches, which was indeed predicted. The other main
group, obtained 97% of the time in 20 740 explored
trees, contained the DIDO PHD sequences clu...
... promoting an increase in
proopiomelanocortin and cocaine and amphetamine
regulated transcript. Taken together, these findings
provide a compelling argument for the role for malo-
nyl-CoA in regulating ... and certain amino acids [16].
A linkage between fatty acid synthesis in the CNS
and feeding behavior was uncovered with the finding
that systemic or intracerebroventricular admin...
... development of principled explanations
of such causal linkages.
Coda
Having begun with a couple of quotations, and having
stressed the role of technology development in science
in general and in systems ... in these pathways, and stresses the role of signal process-
ing (and not merely the intermediates) in biological signalling. It is this
signal processing...
... stability
for crystallins is essential in maintaining lens transparency
[4]. Determining the mechanism of folding and assembly of
these proteins is important for understanding how they can
form stable ... concentrations.
The d
2
-crystallin in lens was recruited during evolution
from argininosuccinate lyase, an enzyme involved in
arginine biosynthesis derived from the urea cyc...
... pivotal role of the UPR is to maintain ER home-
ostasis. Therefore, the presence of mutated proteins
that are unable to fold into their native conformation
in the ER induces the UPR in an effort ... chain is brefeldin A-insensitive and is
inhibited by the proteasome inhibitor clasto-lactacystin
b-lactone, resulting in the accumulation of ricin
A chains. These stabili...
... staining of the gel indicates that
the fluorescing protein is one of the major components of
soluble proteins in the crude extract. The surface of the
fluorescing protein carries negative charge in ... cellular retinal-binding protein; CRBP,
cellular retinol-binding protein; IRBP, interphotoreceptor
retinoid-binding protein; RBP, retinol-binding protein.
Note: The nucl...
... by decreasing the rate of cleavage
between the two subdomains of the A domain. These
findings were later explained with the structural model
that the smaller subdomain A
C
of the A domain
rotates ... important role in
the productive interaction between the A domain and
the PCP domain.
The recently reported crystal structure of a termina-
tion module from the s...
... were raised in rabbits
against a GST-War1p fusion protein containing 294 amino
acids of the C-terminal part of War1p (amino acids 650–
944) fused in- frame to the C-terminus of GST. The gene
fusion ... a binuclear DNA-binding zinc
cluster at the N-terminus, whereas the acidic activation
domain is usually present at the C-terminus. The mid-
dle homology region (MHR) brid...
... defining the set of
items that have ever been the actor in a flight. Their definition is
solely within NIKL using the QUA link [14], which is exactly the set of
fillers of a slot. While having ...
complex theorem proving for expressions in inten-
sional logic. 3
4. Use of the Taxonomy in Janus
By domain mode/we mean the set of axioms en-
coded in NIKL reg...
... the result of the application
of the rule of that node on the resulting S-trees of
its daughters (see figure I).
the donkey is eating apples
-the donkey
the donkey eat apples
donkey R,
eat ... leading to the division of all the rules of the
grammars into (meaningful) rule classes, are along hor-
izontal lines.
These two ways of dividing grammars hav...