Báo cáo khoa học: "INIGATION OF PROCESSING STRATEGIES FOR THE STRUCTURAL ANALYSIS OF ARGOMF" pdf
Báo cáo khoa học: "INIGATION OF PROCESSING STRATEGIES FOR THE STRUCTURAL ANALYSIS OF ARGOMF" pdf
... reception for H must now make use of the tree for the argument built so far and must keep track of propositions whose interpretation is not yet known, 9ending the appearance of their father. The formal ... evidence for a brother or uncle of L - these nodes are closed off, as only the last brother of any particular level is open for further expansion. To determine the appropriateness of this algorithm ... complex for the hearer because he may accept a whole stream of propositions without knowing how they relate to each other until the father for all of them is found. Exa~le: . 9,-~ The reception...
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Báo cáo khoa học: Alternative binding proteins: Anticalins – harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities pdf
... framework of the pairedvariable domains of the light and heavy chains. TheseCDRs come together at the tips of the Y-shaped mole-cule to form a contiguous interface for antigen bind-ing. On the ... bottom of the cleft thatharbours biliverdin IXcin the BBP [24]. Thus, while the overall topology of the lipocalin, comprising the b-barrel with the a-helix attached to it, remained con-served for ... both anticalins, the set of four loops at the entrance to the ligand pocket exhibited pronouncedconformational differences in comparison with eachother and with the BBP. These structural changes...
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc
... assessment of the trajec-tory of interconversion rates as a function of time of cold exposure, (b) comparison of the magnitudes of the various interconversion rates, and (c) lineup of the accessions ... & Stitt M (1993) Reg-ulation of the expression of rbcs and other photosyn-thetic genes by carbohydrates – a mechanism for the sink regulation of photosynthesis. Plant J 3, 817–828.29 Moore ... measure of how exposure to4 °C influenced the process of photosynthesis, gasexchange of plants was measured by infrared gas anal-ysis. Measurements were performed during the first 8 h of the light...
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Tài liệu Báo cáo khoa học: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases pdf
... analyzestopped-flow kinetics for both enzymes [19,20]. The results of the fluorescence titration experiments aresummarized in Fig. 2. In the absence of MgCl2, the affinity of Fpg for the THF:C ligand was ... affect the affinity of the enzyme for the THF:C ligand, its affinity for the THF:A ligand decreased at least 2.3-fold in com-parison with the reactions (C⁄ A specificity for bindingwas 3.5 for 25 ... for the opposite-base specificity of Fpg andOGG1. Also, although the buffering capacity of KGluat pH 7.5 is much weaker than that of KPi, the omission of KPihad a rather minor effect on the...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... basis for structure-activity studies. The highselectivity of the a-conotoxins, together with the possibility of obtaining detailed information on their three dimen-sional structures and the relative ... structures and the relative ease of synthesis, makesthem particularly useful templates for the design of optimized synthetic peptides for the subtype characteriza-tion of nAChRs.AcknowledgementsA. ... snailtissues. The analysis of the DNA of different Conus specieshas already revealed a large number of a-conotoxinsequences [45] and the identification of further specificnAChR ligands is likely. The...
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Tài liệu Báo cáo khoa học: "Enhanced word decomposition by calibrating the decision threshold of probabilistic models and using a model ensemble" pdf
... Another way of classifying ap-proaches is based on the learning aspect during the construction of the morphological model. If the data for training the model has the same struc-ture as the ... algorithm to the improved re-sult? We try to find an answer to this question in the analysis of the subsequent section.3.5 Analysis of calibrated algorithms andtheir model ensemble For the entire ... al.(2001). If the input data has no information to-wards the desired output of the analysis, the algo-rithm uses unsupervised learning. Unsupervisedalgorithms for morphological analysis are...
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Tài liệu Báo cáo khoa học: "Universal Grammar and Lexis for Quick Ramp-Up of MT Systems" doc
... description of the use of all of the above resources is beyond the scope of this paper, we will give a few brief illustrations. The list of English word senses seeds the acquisi- tion of the SL ... resources already developed for the TL. These resources include a) the vocabulary of the generation lexicon which can serve as the list of lexical parameters for compiling the bilingual dic- tionary; ... language, their values are, ulti- mately, all words in the language which belong to the respective lexical categories. The realizations of these values are the specific forms of these words,...
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Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx
... cells to express either the wild-type or mutant proteins, and incubated the cellsin the presence or absence of tunicamycin. Drugtreatments resulted in the accumulation of forms of the mutant proteins ... mutantforms of HFE and incubated the cells in the presenceand absence of tunicamycin. Drug treatment resultedin the accumulation of an unglycosylated lower molec-ular mass form of the wild-type ... at the end of an a-helical region of the HFE a1 domain (V100 and W103A) as being of par-ticular importance for TfR1 interactions [16,17,20]. The effect of HFE binding to TfR1 is to lower the affinity...
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Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf
... new conformation is signifi-cant, as it demonstrates the size of the conforma-tional space of EF-G when not bound to the ribosome. The active conformation of EF-G is the one thatoccurs on the ... structures in the PDB. The structures were superimposed on the basis of domains I and II. Looking from the direction of the arrow in (A) and (B), the coordinates of His572 at the tip of domain IV are ... II. The arrowindicates the direction of projection to the circle in (C). (B) As (A), view 90° away. (C) Comparison of the positions of the tip of domain IV inall available EF-G structures in the...
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Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx
... signaling viaPI3K ⁄ Akt ensures the supply of substrate for lipidsynthesis and enhances the activities of lipogenicenzymes, setting the stage for the accumulation of lipids. Consistent with this, ... composed mostly of complex lipids [49].This could result in the release of FFAs, which thenwould be available for esterification and the formation of triacylglycerols (the main components of LDs). ... induce the up-regula-tion of HIF-1a, most probably via the production of ROS. QDs and the hypoxia mimetic CoCl2down-regulate the oxidation of FFAsand induce the accumulation of lipids. Further...
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