... an bind to p300 and CBP through multiple domains, with a preference of c-Junfor the N- and C-terminal regions and of ATF-2 for the central region of the coactivators.Binding of p50 (amino acids ... the N-, C1- and C2-regions of p300, and to the N- and C2-regions of CBP. Thus, the bulk of the interaction between NF-jB and p300/CBP is mediated by the p65 subunit through the N- and C-terminal ... and p300–C(1571–2370). The intensity of binding, e xpressed as percentage of input bound, is indicated by different shades of gray and only interactionsresulting in binding to more th an 1.5% o f input are...