Báo cáo khoa học: Structures and mode of membrane interaction of a short a helical lytic peptide and its diastereomer determined by NMR, FTIR, and ﬂuorescence spectroscopy pdf

... mode of membrane interaction of a short a helical lytic peptide and its diastereomer determined by NMR, FTIR, and ﬂuorescence spectroscopy Ziv Oren1,*, Jagannathan Ramesh2,*, Dorit Avrahami1, ... maintaining an interface localization of a peptide. In summary, the structural and functional analyses of theall-L-amino acids peptide and its diastereomeric analogindicate that a deﬁned a helical ... capabil-ities have not been determined. In this study we analyze indetail the structural properties and interactions of a modelamphipathic a helical cytolytic peptide and its diastereo-meric analog...

Báo cáo khoa học: Modiﬁed merozoite surface protein-1 peptides with short alpha helical regions are associated with inducing protection against malaria docx

... surface protein-1 peptides with short alpha helical regions are associated with inducing protection against malariaMary H. Torres1*, Luz M. Salazar1*, Magnolia Vanegas1, Fanny Guzman1, ... distance and angular constraints.The calculations were repeated several times until a structure having a minimum of distance and angle restraintviolations and the least root mean square deviation(RMSD), ... jungle.The parasitemia in individual monkeys was measureddaily, starting on day 5 after challenge. Immunoﬂuorescencewas used to evaluate the number of parasites, in terms of thepercentage of parasitized...

Báo cáo khoa học: Structures of the O-polysaccharides and classiﬁcation of Proteus genomospecies 4, 5 and 6 into respective Proteus serogroups ppt

... 2005)doi:10.1111/j.1742-4658.2005.04958.xAn acidic branched O-polysaccharide was isolated by mild acid degrada-tion of the lipopolysaccharide (LPS) of Proteus genomospecies 4 and stud-ied by sugar and methylation analyses along ... obtained in a stand-ard procedures by immunization of New Zealand whiterabbits (two for one bacterial strain) with heat-inactivated(100 °C, 2,5 h) bacteria of Proteus genomospecies 4, 5 and 6, ... h) and was followed by acetylation and GLC analysis as des-cribed above. The absolute conﬁguration of the mono-saccharides was determined by GLC of the acetylated(S)-(+)-2-butyl glycosides according...

Báo cáo khoa học: Structures of Phanerochaete chrysosporium Cel7D in complex with product and inhibitors ppt

... O4 and O5, instead of O5 and O6(Fig. 3B). At the same time, Arg240 can make morefavourable interactions with Gln172 and Asp248. O6now appears to lack a ﬁxed hydrogen-bonding part-ner. The interactions ... O5 and O6 in the +1 siteis thus assumed by Arg251 in Tr_Cel 7A. The main-chain atoms of Arg251 are  3A ˚away from those of Arg240, but the functional guanidino groups aresimilarly placed and ... & ChanzyH (1995) Crystal and molecular structure of beta-d-cel-lotetraose hemihydrate as a model of cellulose II.Macromolecules 28, 2096–2100.32 Panday N, Canac Y & Vasella A (2000)...

Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

... Yonezawa M, Maruyama K, Yamaguchi-Shino-zaki K & Shinozaki K (2007) The mitogen-activatedprotein kinase cascade MKK3-MPK6 is an importantpart of the jasmonate signal transduction pathway ... 565–577.26 Takahashi A, Agrawal GK, Yamazaki M, Onosato K,Miyao A, Kawasaki T, Shimamoto K & Hirochika H(2007) Rice Pti 1a negatively regulates RAR1-dependentdefense responses. Plant Cell ... transformation of intact yeast cells. Nucleic Acids Res 20, 1425.39 Matsuoka D, Nanmori T, Sato K, Fukami Y, KikkawaU & Yasuda T (2002) Activation of AtMEK1, an Ara-bidopsis mitogen-activated...

Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc

... withd-glyceraldehyde; however, DHA was the preferredsubstrate [2]. The A. niger enzyme was commerciallyavailable as a partly purified preparation, and partialamino acid sequence s were available [4].Keywordsdihydroxyacetone; ... Foundation and PR was an Academy ResearchFellow of the Academy of Finland.References1 Baliga BS, Bhatnagar GM & Jagannathan V (1964)Nicotinamide adenine dinucleotide phosphate-specificglycerol ... the analysis. The protein content of the extract was estimated using the Bio-Rad proteinassay, and c-globulin was used as a standard.Enzyme purification and assaysTo purify the histidine-tagged...

Tài liệu Báo cáo khoa học: 1. Signal Transduction 1.1 Integration of Metabolism and Survival pdf

... release from auto-inhibition involves atthe same time a conformational change and its translocation tothe plasma membrane via binding of its tandem SH2 domain tophosphorylated ITAMs. To uncouple ... pylori) and viral (for instance HBV and HCV) patho-gens are major risk factors for certain types of cancer, mostnotably gastric and liver cancers. We have postulated that tran-scription factor ... Italy.E-mail: rosenthal@embl.itThe adult mammalian body does retain the robust repair capa-city of the embryo into adulthood and gradually loses its regener-ative potential. Our approach has...

Tài liệu Báo cáo khoa học: The SCO2299 gene from Streptomyces coelicolor A3(2) encodes a bifunctional enzyme consisting of an RNase H domain and an acid phosphatase domain pdf

... enzyme consisting of an RNase Hdomain and an acid phosphatase domainNaoto Ohtani1, Natsumi Saito1, Masaru Tomita1, Mitsuhiro Itaya1,2 and Aya Itoh11 Institute for Advanced Biosciences, ... 88,12–19.19 Ohtani N, Yanagawa H, Tomita M & Itaya M (2004)Identification of the first archaeal type 1 RNase H genefrom Halobacterium sp. NRC-1: archaeal RNase HI cancleave an RNA-DNA junction. ... Tsuruoka, Yamagata, Japan2 Mitsubishi Kagaku Institute of Life Sciences, Machida, Tokyo, JapanIt is generally accepted that ribonuclease H (RNaseH; EC 3.1.26.4) specifically cleaves an RNA strandof...

Tài liệu Báo cáo khoa học: Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I pdf

... the absence (lanes h–l) or presence (lanes m–q) of equimolar amounts of Akazara scallop TnC. Lanes h and m, ATnI-52K; lanesi and n, ATnI-19K; lanes j and o, ATnI1)128; lanes k and p, ATnI130)252; ... 5230–5240.19 Takeda S, Yamashita A, Maeda K & Maeda Y (2003)Structure of the core domain of human cardiac troponinin the Ca2+-saturated form. Nature 424, 35–41.20 Vinogradova MV, Stone DB, Malanina ... Ca2+; lanes b and e, in the presence of TnC and the absence of Ca2+; lanes c and f, in the presence of bothTnC and Ca2+. Ac, actin; Tm, tropomyosin; RTnC, rabbit TnC; ATnC, Akazara scallop...

Tài liệu Báo cáo khoa học: "Going Beyond AER: An Extensive Analysis of Word Alignments and Their Impact on MT" pdf

... standard technique for evaluating wordalignments is to represent alignments as a set of links (i.e., pairs of words) and to compare the gen-erated alignment against manual alignment of thesame ... Beyond AER: An Extensive Analysis of Word Alignments and Their Impact on MTNecip Fazil Ayan and Bonnie J. DorrInstitute of Advanced Computer Studies (UMIACS)University of MarylandCollege Park, ... data from two language pairsare used in our intrinsic evaluations using the ﬁvecombinations above. A summary of the training and test data is presented in Table 1.Our gold standard for each...

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