... Department of Medicine, Tufts University School of Medicine, Boston, MA, USA3 Department of Biochemistry, Tufts University School of Medicine, Boston, MA, USAOne of the key characteristics of inflammation ... various stages of the multi-step recruitment cascade of leukocytes. The function of inflammatory adhesion molecules can be modula-ted by competitive blockade, altered surface expres-sion of ligands ... type in humans, and accumulate, within hours,at sites of acute inflammation. Once at the site of injury, neutrophils secrete a variety of destructiveenzymes, such as myeloperoxidase, elastase,...