... actin-binding domainThirumaran Thanabalu1,2, Rajamuthiah Rajmohan2, Lei Meng2, Gang Ren4,5, Parimala R. Vajjhala4and Alan L. Munn1,3,4,6*1 Institute of Molecular and Cell Biology, A* STAR Biomedical ... importance of WASP–WIP interaction in mammalian cells is sup-ported by the observation that the vast majority of the disease-causing missense mutations in human WASPmap to the N-terminal WH1 ... and growth atelevated temperature, on the one hand, and in corticalactin-patch polarization, on the other hand, are at leastpartially distinct [23]. However, there may still be a functional...