Báo cáo khoa học: Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis potx
Báo cáo khoa học: Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis potx
... FEBS Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis Paula Maloberti*, Rocı´o Castilla*, Fernanda Castillo, ... shown). Thisresult demonstrates the participation of MTE -I in the regulation of the rate-limiting step in steroidogenesis. To provide additional insights into the sequentialsteps involved in down-regulation ... to the inner mitochondrial membrane. The inhibition of steroidogenesis was overcomeby addition of exogenous arachidonic acid, indicating that the enzymes arepart of the mechanism responsible...
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Tài liệu Báo cáo khoa học: "Exploring the Use of Linguistic Features in Domain and Genre Classification" potx
... recursive partitioning; the splitting criterion was reduction in deviance. Using the Gini index led to larger trees and higher misclassification rates. Since the primary purpose of the trees was ... or infinitive clauses, has been ex- amined selectively in quantitative stylistics. In his comparative analysis of written and spoken genres in English, Biber (Biber, 1988) lists an impressive ... science, both of which tend to contain texts of argumentative types. The frequency of infini- tives of auxiliaries reflects both the use of passive voice, which is formed with the auxiliary "war-...
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Báo cáo khoa học: Hypoxia induces expression of a GPI-anchorless splice variant of the prion protein potx
... Takeshi Yamazaki 4 , Ken-ichi Tanamoto 4 , Haruo Matsuda5, Jun-ichi Sawada2 and Kosuke Takatori11 Division of Microbiology, National Institute of Health Sciences, Tokyo, Japan2 Division of Biochemistry ... regu-lates GPI)PrPSV expression, and its relationship with the expression level of GPI)PrPSV and prion diseasesrequires further investigation.Experimental proceduresMaterialsWe purchased primer ... inhibitor-1(residues 188–200). Plasminogen activator inhibitor-1is an inhibitor of tissue-type plasminogen activator,with which it reacts to form a complex [ 34] . These dataimply an interaction...
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Tài liệu Báo cáo khoa học: Seeking the determinants of the elusive functions of Sco proteins pptx
... eukaryotic Sco proteinsindicate that, despite the full conservation of the threemetal-binding ligands, the metal-binding site has anintrinsic structural flexibility, indicating the absence of a binding ... metal addition. The cysteine ligands are shown inyellow, the histidine ligand in blue, and the Cu (I) ion in light blue.Determinants of the elusive functions of Sco proteins L. Banci et al.2250 ... surface of the hydrophobic residues in human Cu (I) -Sco1 isshown in blue. The cysteines in the CXXXCmotif and the histidine ligand are shown inyellow and green, respectively. The Cu (I) ionis shown...
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Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx
... UDPGlcNAc, and the assay was initiated by addition of these two nucleotides.Where indicated, the assay was initiated by the addition of the enzyme preparation to an otherwise complete assaymixture. The ... 15% of the initial inhibitory activity in the fraction eluted with 500 mm NaCl. As this inhibitoryfraction contained CoASH, we tested the effect of thisnucleotide on glucuronate formation. Like ... forUDP-glucuronidase. This indicates that their activityhas the same type of requirement in terms of phos-pholipidic environment.That the UDP-glucuronidase activity may actuallybe a side activity of...
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Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc
... biosyn-thesis by the action of cycloheximide. Cycloheximidebinds to the 80S-subunit o f eukaryotic ribosomes and prevents the initiation and elongation reaction of proteinbiosynthesis. The mycelium ... diminishespolyketide synthesis or whether a direct interaction of propionyl-CoA with polyketide s ynthetase i s responsible forthis effect.Succinyl-CoA synthetase is directly involved in the degradation ... preventedespecially in a methylcitrate synthase deletion strain by the addition of propionate (Fig. 3, lines III, IV, V and VI). Thiseffect is not observed upon the addition of acetate to the growth medium...
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Tài liệu Báo cáo khoa học: "Modeling the Translation of Predicate-Argument Structure for SMT" ppt
... consider the reorder-ing of an argument as the motion of the argumentrelative to its predicate. In particular, we use the po-sition of the predicate as the reference axis. The mo-tion of associated ... es-timate positions of its associated arguments on the target side. In this way, the model predicts movingdirections of arguments relative to their predicateswith semantic features.We integrate ... study the distribution of argument reorderingcategories (i. e.,NC, L2R and R2L) in the trainingdata, which is shown in Table 3. Most arguments,accounting for 82 .43 %, are on the same side of theirverbal...
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Tài liệu Báo cáo khoa học: "Analyzing the Errors of Unsupervised Learning" docx
... supervised and unsupervised.5 Identifiability errorWhile approximation error is incurred when likeli-hood diverges from accuracy, identifiability error isconcerned with the case where likelihood is indiffer-ent ... the set of maximizers of E log pθ(x)is non-identifiable.8Label symmetry is perhaps the most familiar ex-ample of non-identifiability and is intrinsic to mod-els with hidden labels (HMM and ... optimizing joint likelihood E log pθ(x, y )(generative training) or even conditional likelihoodE log pθ(y | x) (discriminative training).In the remaining sections, we try to study each of the...
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Tài liệu Báo cáo khoa học: "Improving the Scalability of Semi-Markov Conditional Random Fields for Named Entity Recognition" pdf
... undirected graphical models that encodea conditional probability distribution using a givenset of features. CRFs allow both discriminativetraining and bi-directional flow of probabilistic in-formation ... solvedwithout approximation. 4 Reduction of Training/Inference Cost The straightforward implementation of this mod-eling in semi-CRFs often results in a prohibitivecomputational cost.In biomedical documents, ... makes it difficult to enu-merate all the entity candidates in training. Table1 shows the length distribution of entities in the training set of the shared task in 20 04 JNLPBA.Formally, the computational...
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Tài liệu Báo cáo khoa học: "Evaluating the Accuracy of an Unlexicalized Statistical Parser on the PARC DepBank" docx
... constructions, particularlycomparatives and equatives, is limited because of the lack of fine-grained subcategorization infor-mation in the PoS tags and by the need to balancedepth of analysis against ... multiple tag possibilities per word as in-put to the parser, by incorporating lexical subcate-gorization into parse selection, by computing GRweights based on the proportion and probability of ... parsefailures and manually modified the tagger lexiconwhere appropriate. These modifications mostlyconsisted of adjusting lexical probabilities of ex-tant entries with highly-skewed distributions. Wealso...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ