... phosphoinositide-dependentkinase 1; PI3K, phosphoinositide 3-kinase; PKA, protein kinase A; PKC, protein kinase C; PP2A, protein phosphatase 2A; PTP, protein tyro-sine phosphatase, ROCK, Rho-associated kinase; ... SH2-domain-containing inositolpolyphosphate 5-phosphatase (SHIP). Both Akt andKeywordsAkt; protein kinase B; G protein; G protein- coupled receptor; cell cycle; apoptosisCorrespondenceY. H. Wong, Department ... GPCR, G protein- coupled receptor; LPA, lysophosphatidic acid; MAPK, mitogen-activated protein kinase; mTOR,mammalian target of rapamycin; NF-jB, nuclear factor jB; p70S6K, p70 ribosomal protein...