Báo cáo khoa học: cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells pdf

... compilation ª 2006 FEBS 5021 cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells Ana Fernanda Castillo, ... feature in the regu-lation of cholesterol transport by arachidonic acid and the release of arachidonic acid in specialized compartment of the cells could offer novelmeans for understanding the regulation ... mitochondria. The absence of hormone ⁄ cAMP- induced steroidsynthesis when protein synthesis is inhibited can beexplained now by the inhibition in the induction of ACS4 [28] during the early response...

Tài liệu Báo cáo khoa học: An engineered disulﬁde bridge mimics the effect of calcium to protect neutral protease against local unfolding docx

... Ger-many). The amount of intact protein was calculated from the intensity of the protein band.Autoproteolysis in sample solutions containing <20lgÆmL)1protein was followed by determining the ... ± 2.4 kJÆmol)1 through the introduction of the disulﬁde bridge (at5mm CaCl2and 25 ° C) is obtained. The in uence of calcium ions on the unfoldingkinetics The in uence of the calcium ion ... increase in the Gibbs free energy of activation of unfolding undernative conditions. Using the linear extrapolation model[27], the rate constant for the unfolding of G8C ⁄ N60C in the absence of...

Tài liệu Báo cáo khoa học: Molecular cloning, recombinant expression and IgE-binding epitope of x-5 gliadin, a major allergen in wheat-dependent exercise-induced anaphylaxis ppt

... in x-5a gene in Fig. 2, includes all of the detected IgE-binding epitope sequences. Afterampliﬁcation of the DNA encoding this half of the x-5a gliadin protein by PCR, the DNA fragment wasinserted ... contains two stop codonsindicating that x-5b is pseudogene. The C-terminal half (178 amino acids) of the x-5a gliadin protein, including all 11 IgE-binding epitope sequences,was expressed in ... codons are indicated by asterisks. Dashes indicategaps in the alignment. The signal sequences are indicated by underlining. The arrow indicates the region of recombinantly expressed protein.H....

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... disambiguated word meaning. It is the in interaction of the results of these asynchronous processes that the process of comprehension is defined. The processes are independent of the know- ledge ... and in what contexts these morphemes are affected. The study includes off-line picture naming which forces use of articles in all of the above contexts, as well as on-line production of these ... defined than through other methods, because it enables one to develop a broader perspective of the questions within an analysis of the hypothesis in the con- text of a characterization of the...

Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

... help them during the designphase, being able to reuse workﬂows (or parts of them) and thus avoiding reinveinting the wheel.4 Using the tools to work with NLPAll the aforementioned tools were installed, ... combine them in morecomplex chains. These chains are called work-ﬂows and can represent different combinations of tasks, e.g. “extract the text from a PDF docu-ment and obtain the Part of Speech ... on in- stalling new tools when there are other alterna-tives already installed. The paradigm changes considerably with WSs,as in this case only the WSP needs to have a deepknowledge of the installation...

Báo cáo khoa học: Human lactoferrin activates NF-jB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling potx

... pro-tein in the modulation of the in ammatory process [3]. The stimulation of mammalian cells by LPS occurs through a series of interactions with several proteins,including the LPS-binding protein ... resulting in the attenuation of LPS signaling. As LF is known tointeract with LPS, the binding of LPS with LBP mayalso be interfered with in the presence of hLF [9].Although the involvement of ... affect the LPS-inducedactivation of NF-jB (Fig. S4A, B).There is intense interest in the effects of breast-feedingon infants and the mechanisms behind these effects.Compared with formula-fed infants,...

Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

... lysine or arginineresidue. Hence, peptide fragments not featuring alysine or arginine residue in the C-terminal ends ortruncated in the N-termini by some amino acids rela-tive to the preceding ... & Critchley DR (1996) Acidicphospholipids inhibit the intramolecular associationbetween the N- and C-terminal regions of vinculin,exposing actin-binding and protein kinase C phosphory-lation ... that acidic phospholipids inhibit intra-molecular association between the N- and C-terminalregions of vinculin, exposing actin-binding and proteinkinase C phosphorylation sites on serines...

Báo cáo khoa học: Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells pptx

... cells Treatment of serum-deprived ACHN cells withincreasing concentrations of human insulin resulted in a four-fold induction of HO-1 after 6 h (Fig. 1A).Maximal induction of HO-1 protein was achieved ... required for insulin-inducedHO-1 accumulation.Nrf2 translocates to the nucleus following insulintreatment In ACHN cells treated with increasing concentrations of insulin for 1.5 h, the nuclear ... evidence of HO-1 induction byinsulin through the PI3K ⁄ Akt cascade and the Nrf2transcription factor in both transformed renal cells andprimary mouse renal tubular epithelial cells. Insulin-induced...

Báo cáo khoa học: Nigrocin-2 peptides from Chinese Odorrana frogs – integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis pot

... of this generated the C-terminally located mature nigrocin peptide in eachcase. Of major interest was the ﬁnding that the maturepeptides nigrocin-2N, nigrocin-2LVa and nigrocin-2HJare of identical ... feature of nigrocin-2peptides is reminiscent of the glycine ⁄ leucine-richdermaseptin orthologues from the skins of neotropicalphyllomedusine leaf frogs, named plasticins [30].Nigrocin-2 peptides ... MS. Theseinclude peptides previously described as brevinin 1HS,esculentin 1S, esculentin 2S, odorranin C7HSa andodorranin PB.Antimicrobial activity of nigrocin-related peptides The minimum inhibitory...

Báo cáo khoa học: "Estimating Upper and Lower Bounds on the Performance of Word-Sense Disambiguation Programs" docx

... for the machine; it needs all the help it can get. The conditional probabilities, Pr(wlsense), are determined during the training phase by counting the number of times that each word in the ... 100 sets of concordance lines containing one of the test words selected from a single article in Grolier's. The judges were asked to indicate if the set of concordance lines used the same ... discussed in the literature. Note that interest is at the bottom of the list. The reader should exercise some caution in interpreting the numbers in Table 1. It is natural to try to use these...

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