Báo cáo khoa học: Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase doc

Báo cáo khoa học: Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase doc

Báo cáo khoa học: Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase doc

... nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase Nils E. Mikkelsen 1 , Birgitte Munch-Petersen 2 and Hans Eklund 1 1 Department of ... structures of dNK complexed with four dif- ferent nucleoside analogs (floxuridine, brivudine, zidovudine and zalcita- bine) and relate them to the bindin...
Ngày tải lên : 16/03/2014, 06:20
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Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt

Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt

... of rMIH-B at the arthropodial membrane of the periopod and returned to the culture tanks. At 24, 48 and 72 h after injection, the hepatopan- creas and ovary of the shrimp were dissected for total RNA ... monodon. As there is a high degree of sequence similarity and structural conservation of these genes and gene products, confirmation of the true identity and functi...
Ngày tải lên : 16/03/2014, 05:20
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Tài liệu Báo cáo khoa học: Structural features of proinsulin C-peptide oligomeric and amyloid states pptx

Tài liệu Báo cáo khoa học: Structural features of proinsulin C-peptide oligomeric and amyloid states pptx

... amount of oligomers, and this effect was used to investigate the details of both oligomer formation and structure by a combination of bio- physical techniques. The structural properties of the ... distribu- tion of 100 l M proinsulin C-peptide in the presence of divalent Ca 2+ and Mg 2+ ions under native conditions (B), and of 100 l M C-peptide in the presence of i...
Ngày tải lên : 18/02/2014, 04:20
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Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

... case of TIMs from Plasmodium and yeast. Interestingly, the thioether group of M103 is positioned to make a potentially stabilizing contact with the guanidinium group of R99 (equivalent to R98 of ... (equivalent to R98 of PfTIM and yeast TIM). The shortest distance from the sulfur atom of M103 to the NH1 nitrogen of the guanidium group of R99 is 3.23 A ˚ , suggestiv...
Ngày tải lên : 18/02/2014, 11:20
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Tài liệu Báo cáo khoa học: Functional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase Investigations of the putative catalytic glutamate–arginine pair and of residues responsible for substrate specificity docx

Tài liệu Báo cáo khoa học: Functional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase Investigations of the putative catalytic glutamate–arginine pair and of residues responsible for substrate specificity docx

... investi- gated for the multisubstrate Drosophila melanogaster deoxyribonucleoside kinase. Mutation of E52 to D, Q and H plus mutations of R105 to K and H were performed to investigate the proposed ... Munch-Petersen B & Eklund H (2003) Structural basis for feedback inhibition of the deoxyribonucleoside salvage pathway: studies of the Drosophila deoxyr...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: Comparative studies of endonuclease I from cold-adapted Vibrio salmonicida and mesophilic Vibrio cholerae docx

Tài liệu Báo cáo khoa học: Comparative studies of endonuclease I from cold-adapted Vibrio salmonicida and mesophilic Vibrio cholerae docx

... Norwegian Structural Biology Centre, Faculty of Science, University of Tromsø, Norway 2 Department of Molecular Biotechnology, Faculty of Medicine, University of Tromsø, Norway The marine and estuarine ... of VsEndA (Fig. 1). The theoretical pI was 9.61 for VsEndA and 8.62 for VcEndA. Expression and purification From 7 L Escherichia coli culture, a total of 24 and 50 mg...
Ngày tải lên : 19/02/2014, 05:20
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Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf

Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf

... consisting of four copies of four subunits, a, b, c and d. The a and b subunits are regu- latory and are the sites of phosphorylation and meta- bolite binding and are also regulated by the binding of ... II and IV (CaMKI, CaMKII and CaMKIV, respectively), CaM kinase kinase (CaMKK), titin kinase, and death associated kinase [4]. Structural studies on CaMKI...
Ngày tải lên : 19/02/2014, 17:20
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Tài liệu Báo cáo khoa học: "Structural Definition of Affixes from Multisyllable Words" docx

Tài liệu Báo cáo khoa học: "Structural Definition of Affixes from Multisyllable Words" docx

... L. Resnikoff and J. L. Dolby, "The Nature of Affixing in Written English," an algorithm for the structural definition of affixes was developed and applied to data consisting of all ... pected to show up in two-vowel-string words. This paper summarizes the results of applying a modified form of the operational definition to data consisting of all the four...
Ngày tải lên : 19/02/2014, 19:20
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Tài liệu Báo cáo khoa học: "Chronometric Studies of Lexical Ambiguity Resolution " doc

Tài liệu Báo cáo khoa học: "Chronometric Studies of Lexical Ambiguity Resolution " doc

... (the senses of GRASP in " ;to grasp a baseball" and " ;to grasp an idea") or semantically unrelated (e.g., the meanings of TIRE related to "sleeplng" and "wheel"). ... initial access of meaning. Ne suggested such contexts Rrlme one reading of the ambiguous word, in the sense of Collins and Loftus (1975), Meyer and Schvaneveldt...
Ngày tải lên : 21/02/2014, 20:20
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Báo cáo khoa học: Structural evidence of a-aminoacylated lipoproteins of Staphylococcus aureus pot

Báo cáo khoa học: Structural evidence of a-aminoacylated lipoproteins of Staphylococcus aureus pot

... 1420 1409.04 C49 C51 C52 C53 C48 C50 C55 Fig. 3. Triacylated structures of N-terminal peptides of SitC of other three S. aureus strains. MALDI-TOF mass spectra of the organic phase of in-gel tryptic digests of SitC protein, which was isolated through ... of SA2202 from the SA113 strain were prepared and analyzed by MALDI-TOF MS. As shown in Table 2, characteristic peaks corres...
Ngày tải lên : 06/03/2014, 01:20
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