... and functional properties of RNase and participates in degradation of IL-1b mRNADanuta Mizgalska1, Paulina We˛ grzyn1, Krzysztof Murzyn2, Aneta Kasza1, Aleksander Koj1,Jacek Jura3, Barbara ... pro-moter and cDNA for luciferase with or without AREs fromIL-1b cDNA (p-luc )ARE and p-luc), the region flanking the AREs in IL-1b cDNA was amplified using forwardprimer 5¢-ATTCGCTCCCACATTCTGATG-3¢ and ... degradation are in agreement with the results of Matsushita et al. [4]. As for IL-6 mRNA [4], cis-act-ing elements that are important in MCPIP-mediatedIL-1b mRNA degradation are localized in the...