Báo cáo khoa học: Complex gangliosides are apically sorted i

Báo cáo khoa học: Complex gangliosides are apically sorted in polarized MDCK cells and internalized by clathrin-independent endocytosis doc

... complex gangliosides are apically sorted in polarized MDCK cells, and that GD3 and GM1 gangliosides are internalized by clathrin-independent endocytosis to follow different intracellular destinations. Abbreviations CHO, ... participate in the endocytic process of GD3 in MDCK cells. A B C Fig. 5. GD3 and GM1-CTx are internalized in MDCK cells...

Ngày tải lên : 16/03/2014, 04:20

14
305
0

Tài liệu Báo cáo khoa học: Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses pdf

... (B), the side-chains of residues 29, T34 and E131 are shown. The hydrogen bonds between N29 and Oc and T34 and Oc, and between N29 and Nd and E131 and Oe2, in the wild-type protein are shown as green ... the side-chains of Y24, residue 39, F41 and Q149 are shown. The hydrogen bonds between D39 and Od1 and Q149 and Ne, and between D39 and Od2 and Q149 and...

Ngày tải lên : 18/02/2014, 13:20

11
648
0

Tài liệu Báo cáo khoa học: Characterization of electrogenic bromosulfophthalein transport in carnation petal microsomes and its inhibition by antibodies against bilitranslocase docx

... displaying a high- afﬁnity binding site for bilirubin. It is competitively inhibited by grape anthocyanins, including aglycones and their mono- and di-glycosylated derivatives. In plant cells, ... to rat and human ligandins: characterization of a binding-site peptide. Biochim Biophys Acta 955, 296–300. 52 Gregus Z & Klaassen CD (1982) Role of ligandin as a binding protein an...

Ngày tải lên : 20/02/2014, 01:20

15
589
0

Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

... which points to the stabilizing effect of this mutation not being realized in the folding TSE, indicative of the loop between the N-terminal b-hairpin and the main a-helix remaining ﬂexible in the ... A.R. (1991) Protein engineering in analysis of protein folding pathways and stability. Methods Enzymol. 202, 8 2–112. Ó FEBS 2004 Proline residues in ubiquitin stability and foldin...

Ngày tải lên : 07/03/2014, 16:20

11
549
0

Báo cáo khoa học: High levels of structural disorder in scaffold proteins as exempliﬁed by a novel neuronal protein, CASK-interactive protein1 pot

... that can interact with signalling proteins containing SH2 domains. Insulin receptor substrate 1, for example, contains an N-terminal Pleckstrin homology domain and a phosphotyrosine-binding domain, ... regions are often directly involved in protein–protein interactions [42], these points help us to interpret the possible role of disorder in Caskin1 and in other scaffold proteins...

Ngày tải lên : 16/03/2014, 02:20

13
408
0

Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx

... (patatin, found in potato tubers) [28] and iPLA 2 b [23] – iPLA 2 c contains a consensus site for nucleotide binding and a lipase consensus motif in its C-terminal half [26]. Although the intracellular ... mechanisms modulating iPLA 2 c expression and processing in different cell types, we examined multiple iPLA 2 c constructs in different cellular contexts and in intact rat...

Ngày tải lên : 19/02/2014, 16:20

16
438
0

Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf

... extension to the protein kinase folds back on the kinase domain and interferes with the substrate binding sites. In the case of the titin and twitchin kinases, the autoinhibitory sequence acts ... protein kinases including myosin light chain kinase (MLCK), CaM kinases I, II and IV (CaMKI, CaMKII and CaMKIV, respectively), CaM kinase kinase (CaMKK), titin kinase, and death associat...

Ngày tải lên : 19/02/2014, 17:20

12
590
0

Tài liệu Báo cáo khoa học: Type I antifreeze proteins expressed in snailﬁsh skin are identical to their plasma counterparts doc

... solution freezing point noncolligatively by binding to certain surfaces of ice crystals, modifying their structure and inhibiting further growth. The difference between the lowered freezing point and unaltered ... expression only in skin tissue. Taken together, the evidence indicates that the circulating plasma AFPs and skin localized AFPs are identical proteins that are normall...

Ngày tải lên : 20/02/2014, 02:22

10
400
0

Tài liệu Báo cáo khoa học: "Which words are hard to recognize? Prosodic, lexical, and disﬂuency factors that increase ASR error rates" ppt

... (Fosler-Lussier and Morgan, 1999; Shinozaki and Furui, 2001) and that fast speech increases error rates (Siegler and Stern, 1995; Fosler-Lussier and Morgan, 1999; Shinozaki and Furui, 2001). Siegler and ... with Shinozaki and Furui (2001) and Siegler and Stern (1995). The effects of pitch minimum and maximum are not shown for reasons of space, but are similar to pitc...

Ngày tải lên : 20/02/2014, 09:20

9
441
0

Báo cáo khoa học: Many fructosamine 3-kinase homologues in bacteria are ribulosamine⁄erythrulosamine 3-kinases potentially involved in protein deglycation docx

... Xyluloselysine was synthesized as described for ribuloselysine and fructoselysine was synthesized as previously described [2]. Pentitollysine was prepared by incubating (in 0.1 mL) 50 mm ribuloselysine ... recombinant fructosamine 3-kinase (FN3K) and low-molecular-weight protein-tyrosine-phosphatase (LMW- PTP) homologues. Restriction sites are written in italics. ATG and stop cod...

Ngày tải lên : 07/03/2014, 05:20

15
533
0