Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf

Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf

Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf

... Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile Sudeep Bhattacharyya, Amy Kerzmann and Andrew L. Feig Department of ... sugar complexes for use in studying glycosyl- transferases in general and TcdA in particular. These substrate analogs are related to the commercially...
Ngày tải lên : 08/03/2014, 22:20
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Báo cáo Y học: Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types pptx

Báo cáo Y học: Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types pptx

... CD53, can have a signalling role by themselves. Natural ligands of CD53 or other tetraspan proteins are not yet known. In a way tetraspanin proteins can be considered as orphan receptors, and consequently ... immunoprecipitate by the incorporation of radioactivity in the GST–ATF2 fusion protein used as substrate. At the top is the assay of the tran sfected HA-JNK activity...
Ngày tải lên : 08/03/2014, 22:20
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Báo cáo Y học: Domain V of m-calpain shows the potential to form an oblique-orientated a-helix, which may modulate the enzyme’s activity via interactions with anionic lipid potx

Báo cáo Y học: Domain V of m-calpain shows the potential to form an oblique-orientated a-helix, which may modulate the enzyme’s activity via interactions with anionic lipid potx

... divided into domains V and VI. Domain II possesses the active site and is a papain-like cysteine protease domain, and domain IV contains a calmodulin-like Ca 2+ -binding domain with multiple EF-hand ... damage, and neurodegenerative con- ditions such as Alzheimer’s and Parkinson’s disease [10,11]. The major calpains are l-calpain (calpain 1) and m-calpain (calpain 2), which...
Ngày tải lên : 17/03/2014, 10:20
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Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

... between both assays is the coupling of AR.NTD to GalAD in the yeast assay, and the absence of a second transactivation domain linked to AR NTD in the mammalian assay. The latter assay completely depends ... the 23 FQNLF 27 motif in AR N/C interaction, these amino acids were substituted by 24/25AA. In both the yeast and mammalian protein interaction assay, GalAD- AR.NTD24/2...
Ngày tải lên : 17/03/2014, 10:20
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Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf

Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf

... mutagenic primer was 5¢-GGAAATC ACACCATTATGACCA AAAACCAGCCCGGGATA GGC-3¢. The underlined codons code for bF24 and bF57 and were changed to ATA, CCA, AGC and CAA to introduce Tyr, Trp, Ala and ... acylation by PGA in a similar way as the acylation by NIPAB. A notable exception was the twofold increased activity for PGA of the aF14 6Y mutant. It appeared that this mutant ha...
Ngày tải lên : 17/03/2014, 23:20
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Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf

Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf

... (NdeIorBglII). aac Oligonucleotide sequence aac1 (A. t.) Sense 5¢-TGCAGAGTTCcAtATGGTTGATCAAG-3¢ Antisense 5¢-CGAAAAAAGGAGGAAGAAGCAATGC-3¢ aac2 (A. t.) Sense 5¢-TGTAGAGGTTcAtATGGTTGAACAGACTC-3¢ Antisense ... 5¢-TGTAGAGGTTcAtATGGTTGAACAGACTC-3¢ Antisense 5¢-CTTAATGACTGCGGGATTTGGTGGTAC-3¢ aac3 (A. t.) Sense 5¢-CTGATTTGTACAAcAtATGGATGGATC-3¢ Antisense 5¢-GGGCTATTCTTTCATCATCCTCATCG-3¢ aac1 (S.t.)...
Ngày tải lên : 18/03/2014, 01:20
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Báo cáo Y học: The evolution of monomeric and oligomeric bc-type crystallins potx

Báo cáo Y học: The evolution of monomeric and oligomeric bc-type crystallins potx

... sequences, and of a hydrophobic residue in c-type crystallins. Contrasting results were obtained in another laboratory, showing that a recombinant b-crystallin variant is isolated as a dimer also when ... presence of spliceosomal introns in eukaryotes, and their absence in archea and in eubacteria [38–40]. Over recent years, a vast amount of data has been inter...
Ngày tải lên : 24/03/2014, 04:21
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Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

... lead concentrations may be increased in patients with CAD. Key words: coronary artery disease; trace element; heavy metal; vitamin INTRODUCTION Coronary artery disease (CAD) is a leading cause ... patients hav- ing angiographically demonstrated CAD and 20 pa- tients having normal coronary arteries attending car- diology clinic at Yuzuncu Yil University Hospital. The study was appro...
Ngày tải lên : 25/10/2012, 10:51
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Tài liệu Báo cáo khoa học: "Automatic Identification of Pro and Con Reasons in Online Reviews" ppt

Tài liệu Báo cáo khoa học: "Automatic Identification of Pro and Con Reasons in Online Reviews" ppt

... contain topics in a text have cer- tain positional patterns in a paragraph (Lin and Hovy, 1997), which may apply because reasons like pros and cons in a review document are most important ... you are in a train station or a busy amusement park that is ill-staffed to meet de- mand!”, “preferential treatment given to large groups”, and “they don't offer salads...
Ngày tải lên : 20/02/2014, 12:20
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Báo cáo khoa học: Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I pdf

Báo cáo khoa học: Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I pdf

... Spain Introduction Primary hyperoxaluria type I (PHI) is a rare autosomal recessive disease caused by mutations in the alanine-gly- oxylate aminotransferase gene (AGXT). Alanine-glyoxy- late aminotransferase ... favored over aminobutyrate-pyruvate, b-alanine-pyruvate and dimethylarginine-pyruvate aminotransferase activities. In the rat, gluconeogenesis from l-serine takes place ma...
Ngày tải lên : 23/03/2014, 03:20
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