Báo cáo khoa học: "Conceptual Analysis of Garden-Path Sentences" ppt

... in a number of ways, the simplest of which is the notion of one word preceding or following another. Such information is encoded as a positional predicate in the test of a type of production ... semantic features of "boat s and finds that they match the selectional restrictions required of the subject of "sail'. The action of this request is executed, in spite of the fact ... etc. [The usage of "subject" is incorrect in the usual sense of the word.) The Time facet of REQ2a states that the request should be considered only after the type of the clause is...

Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx

... Department of Structural and Functional Biology, and Centre of Neuroscience, University of Insubria, Busto Arsizio, Italy2 Department of Biotechnology, University of Verona, Italy3 Department of Clinical ... speciﬁcally linked to one of the major patho-genetic mechanisms of PD [5]. Worthy of note is thecomplete disappearance of the VDAC-2 upon dopa-mine treatment. This porin of the outer mitochondrialmembrane ... Sciences, University of Insubria, Varese, Italy4 Department of Neuroscience, University of Torino, ItalyIntroductionParkinson’s disease (PD) is a sporadic neurodegenera-tive disorder of unknown etiology...

Tài liệu Báo cáo khoa học: Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters pdf

... hydrolysis of o-NTFNAC was recorded at 430 nm(e = 3954 m)1Æcm)1) for 5 min.Acetyl estersKinetic analysis of the BuChE-catalysed hydrolysis of o-NPA was followed by monitoring the rate of appearance of ... DiscussionAction of reversible effectors on AAA activity of BuChEThe investigation of the effects of the ligands(tyramine, serotonin and benzalkonium) on the AAAand esterase activities of BuChE was ... higherconformational plasticity of the active site gorge of D70G compared with that of the wild-type enzyme foracylation with neutral ester.Effects of benzalkonium on ATMA hydrolysisHydrolysis of ATMA by wild-type...

Tài liệu Báo cáo khoa học: Quantitative analysis of the experimental O–J–I–P chlorophyll ﬂuorescence induction kinetics Apparent activation energy and origin of each kinetic step Steve Boisvert, David Joly and Robert Carpentier doc

... series of succes-sive events that lead to the progressive reduction of the quinone molecules located on the acceptor side of PSII [3].The progressive reduction of the acceptor side of PSII ... superposition of the exponential rise to analyzequantitatively the contribution of each phase. Theamplitude and rate constant of each of the threephases can be calculated by deconvolution of thetraces ... thylakoids in the absence of additives orin the presence of 1 lm DCMU or dPQ over a range of temperature from 15 °Cto25°C. The range of tem-perature was set on the basis of the membrane trans-ition...

Tài liệu Báo cáo khoa học: Thermodynamic analysis of porphyrin binding to Momordica charantia (bitter gourd) lectin pptx

... theinteraction of several water-soluble porphyrins with MCL.The thermodynamic forces governing the interaction of some of the porphyrins have been delineated from an analysis of the temperature ... (in subunits). Inset: plo t of 1/DA as a function of thereciprocal total pro tein concen tration. T he reciproca l of the Y-in ter-cept of this plot gave th e value of DA1, the change in a ... shown. A ﬁ t of the CDspectrum of native MCL, obtained by analysing thespectrum using theCDSSTRprogram, is also given (details of the spectral analysis are given b elow). The spectrum of MCL in...

Tài liệu Báo cáo khoa học: Subproteomics analysis of Ca2+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle pdf

... viscosity of t he extract as a result of D NA, 2 lLofDNase I (200 units) was added per 100 lL of buffer [30].Following filtration through two layers of miracloth a nd theaddition of four volumes of ... ÔStains-AllÕ analysis of Fig. 3 and the 1D i mmunoblotting of Fig. 4.As the full-length Dp427 isoform of dystrophin does notenter the second dimension of conventional 2D gels, theexpression level of ... ypothesis of muscular dystrophy [20–22]. Deficiency in the D p427isoform o f d ystrophin r esults in the r eduction of a specificsubset of sarcolemmal glycoproteins [23,24]. The lack of the s...

Tài liệu Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation ppt

... E-box.Substitution of Arg65 for Ala abolished the interaction of DEC1 with BMAL1 and the binding of DEC1 to the E-box.However, substitution of His57 for Ala did not affect theinteraction of D EC1 w ... Kato11Department of Dental and Medical Biochemistry, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan;2Department of Physiology, Hokkaido University Graduate School of Medicine, ... for the rhythmic expression of Dec1, and the feedback loop of DEC1 (as well as that of BMAL1) might be interlocked with the core feedback loopto constitute a network of the circadian clock system[11,12,14]....

Tài liệu Báo cáo khoa học: Mutational analysis of plasminogen activator inhibitor-1 Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition pdf

... Formation of the covalent serpin–protease complex involves a Michaelis docking complex,cleavage of the P1–P1¢ peptide bond, linkage of the activesite Ser of the protease to the carboxyl group of ... shown is a typicalone out of a total of at least three.Ó FEBS 2003 Mutational analysis of PAI-1 (Eur. J. Biochem. 270) 1685PAI-1 (N152A) all showed a biphasic loss of activitysuggesting a heterogeneity ... Mutational analysis of plasminogen activator inhibitor-1Interactions of a-helix F and its neighbouring structural elements regulatesthe activity and the rate of latency transitionTroels...

Tài liệu Báo cáo khoa học: Fluorescence analysis of the Hansenula polymorpha peroxisomal targeting signal-1 receptor, Pex5p pdf

... 348.8 nm. Analysis of the fluorescence intensity decay and anisotropy decay wasperformed with a model of discrete exponentials using theTRFA Data Processing Package of the Scientific SoftwareTechnologies ... conformational properties of HpPex5p, the PTS1receptor of the yeast H. polymorpha. Fluorescence emissionspectra revealed a pH dependence of Trp fluorescence of HpPex5p, indicative of pH driven changes ... concludedfrom the structural model of the PTS1-bindingC-terminal domain of HpPex5p (Fig. 4). In this domainthree of the seven Trp residues of HpPex5p are found.However, of these three residues only...

Báo cáo khoa học: Thermodynamic analysis of Jun–Fos coiled coil peptide antagonists pdf

... Seldeen KL, Mcdonald CB, Deegan BJ & Farooq A(2008) Thermodynamic analysis of the heterodimeriza-tion of leucine zippers of Jun and Fos transcription fac-tors. Biochem Biophys Res Commun 375, ... AK & Hodges RS (1984) Synthesis of a model protein of deﬁned secondary and quaternarystructure. Effect of chain length on the stabilization andformation of two-stranded alpha-helical coiled-coils.J ... FEBSThermodynamic analysis of Jun–Fos coiled coil peptideantagonistsInferences for optimization of enthalpic binding forcesJonathan A. R. Worrall and Jody M. MasonDepartment of Biological Sciences,...

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