Báo cáo khoa học: "CONTROL STRUCTURES AND THEORIES OF INTERACTION IN SPEECH" potx

... kinds of interaction which occur between component.% that is. none of them are based on any theory of what kind of interactions and eomrnunication will be needed in a SUS. The designers of ... CONTROL STRUCTURES AND THEORIES OF INTERACTION IN SPEECII UNDEP~.WI'ANDING SYSTEMS E.J. Briscoe and B.K. Boguraev University of Cambridge, Computer Laboratory ... criticism in ]Iayes-l~.oth, 1983a:55). I INTERACTIVE DETERMINISM: A THEORY OF NON-SERIAL INTERACTION In this section, we concentrate on the study of NSI between morphosyntactm and prosodic information...

Báo cáo khoa học: "Automatic Detection and Correction of Errors in Dependency Treebanks" potx

... annotations, e.g. labels, POS tags etc. In fact, in the area of POS tagging a similar strategy of using the same data for training and testing in order to detect inconsistencies has proven to be ... idea behind this step is that we basically try to repro-duce the gold standard, since parsing the data seen during the training is very easy (a similar idea in the area of POS tagging is very ... Penn Treebank [1] have thousands of citations, since most of the algorithms profit from annotated data during the development and testing and thus are widely used in the field. Treebanks are...

Báo cáo khoa học: Identiﬁcation and localization of glycine in the inner core lipopolysaccharide of Neisseria meningitidis ppt

... oligosaccharide of meningococcal LPS.MATERIALS AND METHODSGrowth of organism and isolation of LPSN. meningitidis immunotype strains L3 galE (NRCC #4720) and L4 galE (NRCC #4719) and clinical strains BZ157 ... 2002 Glycine in meningococcal LPS (Eur. J. Biochem. 269) 4171also performed on two other meningococcal strains of clinical origin and the compositions of the glycoformsobserved are listed in Table ... Inova 500 spectrometer and was of the order of 15 h. The13C–1H coupling constant was140 Hz, with a sweep width in the F2 (1H) dimension of 10.0 p.p.m. and in the F1 (13C) dimension of...

Báo cáo khoa học: Gene duplication and separation of functions in aB-crystallin from zebraﬁsh (Danio rerio) pptx

... lens pro-tein. A single spot containing both zebrafish aB1 and aA-crystallin was identified by comparing its positionwith a sample of recombinant proteins run in parallel,as well as probing with ... electrophoresis of zebrafish lens protein. The spotscontaining both zebrafish aA-crystallin and aB1-crystallin, zebrafishaB2-crystallin and modifications or truncations of a-crystallins areindicated. ... found in the twoother fish proteins but shares two of the three serinephosphorylation sites present in bovine aB-crystallin,while zebrafish aB1 contains only one. The arginineat position 120 in...

Báo cáo khoa học: Molecular structures and functional relationships in clostridial neurotoxins potx

... because of the single chain molecule. Theposition of the binding domain of E could be obtainedby rotating the binding domain of A or B about the lin-ker region connecting the translocation and bindingdomains. ... globular (Fig. 12). In BoNT ⁄ A and Bthere are only limited interactions between the translo-cation and binding domains and no interaction betweenthe binding and catalytic domains. In BoNT ⁄ E, all ... domain of type A(1–844 of E and 871–1296 of A) acts as fast asBoNT ⁄ E, whereas chimera AE containing the catalytic and translocation domains of type A and the bindingdomain of type E (1–874 of...

Tài liệu Báo cáo khoa học: Afﬁnity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx

... carried out in single-point binding assays at high initial cell density.Binding-inhibition experimentsCells grown in 12-well plates were washed once with 1 mL of DMEM and incubated in the same ... affinity and kinetics of binding of PCSK9 to LDLR on HepG2 cells at 4 °C. The extent of [125I]TC-PCSK9 binding increased as cell surface LDLR densityincreased. Unlabeled wild-type and two gain -of- function ... mutants of PCSK9 reduced binding of [125I]TC-PCSK9. The Scatchard plot of thebinding-inhibition curve was curvilinear, indicative of high-affinity and low-affinity sites for PCSK9 binding on...

Tài liệu Báo cáo khoa học: Identiﬁcation and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebraﬁsh, Danio rerio docx

... seen in the putative T-boxDNA-binding domain of t-bet, the STAT protein inter-action domain, STAT protein all-alpha domain, STATprotein DNA-binding domain and SH2 domain of stat6, and the zinc-ﬁnger ... FOX proteins, a leucine zipper domain and a C2H2 zinc ﬁnger domain, both of which arethought to help mediate DNA binding and may beinvolved in the induction of dimerization [43]. Each of these ... expression of T-bet has beenseen within a wide variety of tissues and cells in theGinbuna crucian carp [27] and, in mammals, in thelung tissue of mouse and spleen and thymus of human and mouse...

Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulﬁde isomerase family proteins with nonclassic active center motifs pdf

... processing), and GmPDIL-1 and GmPDIL-2 associate with proglycinin and b-con-glycinin in the ER, suggesting that they may playimportant roles in folding and in formation and rearrangement of disulﬁde ... synthesis levels of both b-conglycinin and glycinin,as pro-b-conglycinin and proglycinin are transient pro-tein forms that are present in the ER prior to process-ing in the protein storage vacuoles. ... The synthesis of proglycinin and pro-b-conglycinin was initiated whenthe seeds achieved a mass of 50 mg (Fig. 5A, lanes 2 and 4). The amount of GmPDIL-3a and GmPDIL-3bproteins increased until...

Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt

... contribute todiabetes include exocytosis of insulin-containing gran-ules by uncoupling protein-2 through ATP consump-tion, and granuphilin through inhibition of the vesiclefusion machinery [29–31].Fatty ... activation of the sterol regulatory element-binding protein cleavageactivating protein ⁄ sterol regulatory element-bindingprotein pathway. Mol Endocrinol 15, 1817–1828.13 Yang YA, Morin PJ, Han ... signaling molecule in the liver and pancreatic b-cells [8,26]. Suppression of IRS-2 bySREBP-1c in the liver inhibits processes regulatinginsulin signaling, such as glycogen synthesis, and con-tributes...

Tài liệu Báo cáo khoa học: Identiﬁcation and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni pdf

... representing the 5¢- and 3¢-UTRs areshown in white in the genomic gene and the cDNA. Intron size in bp, domain size in bp and domain size in amino acids are indicated at thebottom of each schematic ... address these interactions in in vitro and in vivo surrogate systems. In this study, protein interaction experiments havedemonstrated that SmSmad1B and SmSmad1 sharesimilar binding properties. ... was included in the reactions, a reduction in interaction level with GST-SmCBP1 was observed withboth SmSmad1 and SmSmad2 (Fig. 10B), and again,Fig. 8. In vitro interaction between SmSmad1B and...

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