... widespread and centralclass of sexual development factors in fishAmaury Herpin and Manfred SchartlPhysiological Chemistry I, University of Wuerzburg, GermanyIntroductionThe phenomenon of two ... Consideringthat dmrt1bY has all the features of the master regula-tor of testicular differentiation in medaka (see [13] forreview) and because of the discovery of sex-chromo-some-linked dmrt1s in ... molecu-lar activity of Sry is translated into cellular structure and organ morphology. Interestingly, Dmrt1, theancestor of Dmrt1bY, is one of the downstream effec-tors of Sry in the male pathway.In...