Báo cáo khoa học: "Recognition of the Coherence Relation between Te-linked Clauses" potx

... event. The notion of the manner is continuous to the means since the means and manner of an event are often coextensive in that the means of an event often determines the manner of the event. ... diversity of relations arise in the next section. 3 Organization of the Coherence Relations Although the semantic relations between the re- linked constituents are diverse, not all relations ... Examples of the linking rules Figure 1: The organization of the relations with te- linkage that this organization of the relations are viewed from the perspective of re-linkage. The different...

Báo cáo khoa học: Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase pptx

... dithionite in the absence of oxygen, and recording of the spectra of the reduced states was repeated. To investi-gate the effect of the mutations on the ﬂavinylation state of the P2O variants, ... distance of 14 A˚ between the 2FG glucosyl and Trp456indole rings. On the basis of the position of the side chain and itsremote location from the ligand in the Y456W2FGstructure, the Trp456side ... Asp452Od1–Asp470Od2,Asp452Od1–Arg472Ng1).Comparison of the active-site volumesTo determine whether there are changes in the volume of the active site as a result of mutations that mayexplain the ability to accommodate substrates otherthan...

Báo cáo khoa học: " Effect of the medical emergency team on long-term mortality following major surgery"

... suffered at least loss of one rel-ative, for example, a partner or child, and two mothers of ourcohort lost both of their children. The majority of patients com-plained of nightmares, emotional ... aftermathWith respect to the tsunami's psychoemotional aftermath, the full impact of the wave on the mental health of the survivors isstill unknown [2]. In February 2005 the World Health Organi-zation, ... Department of Psychotraumatology of the University of Heidelberg (Germany) assembled a comprehen-sive list of 400 qualified psychotherapists offering immediatesupport nationwide when needed. These...

Tài liệu Báo cáo khoa học: Motion of the Ca2+ -pump captured ppt

... as the ATP-unbound and Ca2+-boundE1Ca2+form. In the histogram (Fig. 2A) of the dis-tribution of the height of the projection of the embed-ded molecule above the ﬂat membrane surface, the average ... Histograms of the height differences between the top of SERCA and the surface of the membrane. Statistical section analy-ses of SERCA were performed with the data obtained in the pres-ence of (A) ... presence of both ATP andCa2+were excluded from the following analyses.Visual characteristics of the Albers–Post scheme The number of peaks (i.e. the number of up–downconformational changes of...

Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx

... result of the lengthrestrictions of this minireview. The work of S.W. wassupported by the Deutsche Forschungsgemeinschaft(We2843 ⁄ 2-1) and BGAG-Stiftung Walter Hesselbach. The work of S.B. ... thatthere is a controversy in the literature about the impor-tance of the CagL RGD-motif in T4SS functions andhost cell signalling. Another unsolved question is the proposed structure of CagY ... by T-pilus assembly. The assem-bled T4SS then triggers the secretion of substrates from the bacterial cytoplasm directly into the cytoplasm of infected host cells or into the extracellular milieu....

Tài liệu Báo cáo khoa học: Upregulation of the a-secretase ADAM10 – risk or reason for hope? docx

... that the prodomain of ADAM10 acts not only as a transientinhibitor, but also as an internal chaperone in the mat-uration of the enzyme. Accordingly, the viral delivery of furin into the brain of ... point of intervention within the biosyntheticpathway of ADAM10 is provided by directly interfer-ing with the expression of the gene for ADAM10: the promoter region of the gene for ADAM10 has beencharacterized ... treatment of AD, enhance the transport of ADAM10 to the cellsurface and the non-amylodogenic cleavage of APP[91,92].ADAM10 has also been shown to be regulated by the lipid composition of the plasma...

Tài liệu Báo cáo khoa học: Myristoylation of the dual-speciﬁcity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf

... preferentially the phosphorylation of the p46 isoform of JNK,whereas sorbitol treatment induced phosphorylation of both the p46 and p55 isoforms. To conﬁrm functionalactivation of the JNK signaling ... phosphorylation of the transcription factorc-JUN was attenuated. Upon expression of wild-type JSP1, a subpopula-tion of cells, with the highest levels of the phosphatase, was induced toﬂoat off the dish ... intrinsic phosphatase activity in the absence of myristoylation, the subcellular localization of the enzyme was altered.Compared with the wild type, the ability of nonmyristoylated JSP1 toinduce...

Tài liệu Báo cáo khoa học: Regulation of the members of the mammalian heat shock factor family doc

... development of the lens and maintenance of the olfactory epithelium [102]. The ﬁrst evidence for a developmental function of HSF4 was provided by population genetic studies wheremutations of the Hsf4 ... how the developmental activity of HSF1 isregulated. The identity of the developmental signalthat promotes a monomer-to-trimer transition of HSF1 in the olfactory epithelium warrants furtherinvestigations. ... accordance with the fundamentalrole of HSF1 in the heat shock response, the require-ment of HSF1 and HSF4 in development of the lensand olfactory epithelium is limited to the postnatalperiod,...

Tài liệu Báo cáo khoa học: Structure of the putative 32 kDa myrosinase-binding protein from Arabidopsis (At3g16450.1) determined by SAIL-NMR docx

... 5875Comparison of NMR spectra of SAIL and ULAt3g16450.1Although the concentration of the SAIL protein waslower than that of the UL protein by a factor of three(SAIL, 0.2 mm; UL, 0.6 mm), the NMR ... of SAILFig. 3. Secondary structure of At3g16450.1. (A) Ribbon representa-tion of the NMR structure of At3g16450.1. These ﬁgures were pre-pared usingMOLMOL [25]. Due to the lack of NOEs, the ... from inter-nal dynamics of these residues on the intermediate timescale for chemical shifts. As a result, these are the leastwell-deﬁned regions of the N-terminal domain. The C-terminal domain...

Tài liệu Báo cáo khoa học: Switching of the homooligomeric ATP-binding cassette transport complex MDL1 from post-translational mitochondrial import to endoplasmic reticulum insertion pptx

... inter-acts with the TOM receptor, responsible for the trans-location of the preproteins to the translocase of the inner mitochondrial membrane (TIM)23 complexlocated in the IMM. The presequence ... hydrolysis in the nucleotide-binding domain of the ABC transporterHlyB. EMBO J 24 , 1901–1910.38 Kuhnke G, Neumann K, Mu¨hlenhoff U & Lill R (2006)Stimulation of the ATPase activity of the yeast ... proteins [14]. The mitochondrial targeting signal (MTS) of pro-teins directed to the IMM is recognized by receptors of the translocase of the outer mitochondrial mem-brane (TOM complex). The classical...

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