... compilation ª 2006 FEBS 1619
MINIREVIEW
DNA mismatch repair system
Classical and fresh roles
Sung-Hoon Jun, Tae Gyun Kim and Changill Ban
Department of Chemistry and Division of Molecular & Life ... [22]. DNA polymerase III, single-stranded
DNA- binding protein and DNA ligase carry out repair
synthesis [3].
Eukaryotic mismatch repair
All eukaryotic organis...
... suppressor
genes and inactivation of DNA repair systems are a
result of both genetic and epigenetic abnormalities.
The correlation between the status of -CpG-island
hypermethylation and ⁄ or mutations ... the
other hand. EGCG can bind to GpC-rich regions of DNA. Radiation can damage the respective genes, thereby inviting repair enzymes [2].
This facilitates repair- based DNA d...
... homologous pairing and strand exchange during
homologous recombination and double-strand break
repair [1,2]. Rad51 and Rad52 colocalize in distinct
nuclear foci in response to DNA damage [3]. Yeast
rad52 ... recombinational repair machinery to
a DNA double-strand break in yeast. Mol Cell 12,
221–232.
8 Benson FE, Baumann P & West SC (1998) Synergistic
actions of Rad51 andRad...
... as
gold standard roles and training data. More re-
cent learning work has applied bootstrapping ap-
proaches (Swier and Stevenson, 2004; He and
Gildea, 2006), but these still rely on a hand la-
beled ... roles have required a pre-defined set of
roles (Grenager and Manning, 2006) and often a
hand-labeled seed corpus (Swier and Stevenson,
2004; He and Gildea, 2006).
In this p...
... and HinfI for 3 h and recovered by
ethanol precipitation. The precipitated DNA was dissolved
in 3 lL of water and added into the ligation mixture
[100 ng each of landmark- and HinfI-adapter and ... restric-
tion-modification systems, which distinguish self and
nonself DNA to protect bacteria from invaders. In this
system, the host DNA is methylated and only unmeth-
ylated...
... DNA without any protein; lanes 2, 3
and 4 correspond to DNA complexes with p53(1–363), p73d and p73b, yielding retarded bands R
53
,R
73d
and R
73b
, respectively. In lanes 5–7,
the protein DNA ... one strand and two AG steps in the other. The
mdm2 target, whose interaction with p53 was most
strongly affected by DNA cis-platination, contains
GG, GGG and AG motifs in one stran...
... of
single-strand DNA (ssDNA) and assimilation of ssDNA
into homologous super-coiled duplex DNA. J Biol
Chem 276, 41906–41912.
10 Nara T, Hamada F, Namekawa S & Sakaguchi K (2001)
Strand exchange ... 2006)
doi:10.1111/j.1742-4658.2006.05170.x
Rad51 and disrupted meiotic cDNA1 (Dmc1) are the two eukaryotic DNA
recombinases that participate in homology search and strand exchange
r...
... repair to Denver replaces the reparandum.
Shriberg and Stolcke (1998) studied the location
and distribution of repairs in the Switchboard cor-
pus (Godfrey and Holliman, 1997), the primary cor-
pus ... explicit editing terms (e.g., “I mean”), par-
enthetical asides and repairs. Of these, repairs
pose particularly difficult problems for parsing and
related Natural Language Processin...
... brows-
ing and retrieval system. The prototype
is in an early stage of development, and
we are currently exploring the role of nat-
ural language for interacting in this rela-
tively unfamiliar and ... unfamiliar and complex domain. We
briefly describe the design and implemen-
tation status of the system, and then focus
on how this system is used to elicit useful
data for suppo...