... picolinicacid (PA), quinolinic acid (QA) and NAD homeostasis. Indeed, the enzymestands at a branch point of the tryptophan to NAD pathway, and deter-mines the final fate of the amino acid, i.e. transformation ... Regulation of mouse hepatic a- amino-b-carbo-xymuconate-e-semialdehyde decarboxylase, a keyenzyme in the tryptophan–nicotinamide adenine dinu-cleotide pathway, by hepatocyte nuclear factor 4a andperoxisome ... nonoxidative decarboxylation catalysed by a- amino-b-carboxymuconate-e-semialdehyde decarbox-ylase. J Am Chem Soc 129, 9278–9279.20 Fukuoka SI, Ishiguro K, Yanagihara K, Tanabe A, Egashira Y, Sanada...