... modification on the catalytic
activity of deoxyribozyme 10–23
The functional role of the individual phosphate groups
in the catalytic core of deoxyribozyme 10–23 was
examined by determination of the thio ... deoxyribozyme 10–23
In order to obtain a deeper insight into the functional
role of the oxygen atoms of the P5 phosphate group...
... receptor–ligand
interactions of the histamine receptors. Elucidation of the
structure and dynamics of membrane proteins is a challen-
ging task essential for proper understanding of the func-
tioning of fundamental ... [28].
The N-terminal sequence of the H1 receptor indeed contains
two N-linked glycosylation consensus sites, but in prelim-
inary studies no binding to...
... production of inter-
leukins and secretion of immunoglobulins on the
mucosal surface of the intestine [49,50]. The antibacte-
rial defence of the intestinal mucosa depends in part
on stimulation of CCK ... euge-
nin, indicating that eugenin is indeed acting through
CCK
2
receptors.
To further investigate the interaction of eugenin with
CCK
2
receptors, we investigated...
... terminal in the grammar. If A
is a terminal then G
A
is the distribution that puts all
of its mass on the unit tree (i.e., tree consisting of a
single node) labeled A. If A is a nonterminal then
G
A
is ... parse of that
string with a PCFG approximation to the adaptor
grammar. This PCFG contains a production for each
adapted subtree in the parses of the other strings i...
... that the RPEL domain of MRTF-A binds
actin more strongly than the RPEL domain of myocar-
din, and that the RPEL motif itself is an actin-binding
element. RPEL1 and RPEL2 of myocardin bind actin
weakly ... as
STARS-interacting proteins. These novel proteins con-
tain four LIM domains and a C-terminal villin head-
piece domain, which mediates actin-binding in several
proteins, suc...
... written in the form of appropriate tables
of rules. The paper raises the question of the increasing complexity of
the tables when more than the most elementary natural-language con-
ditions are included, ... machine translation.
It must be noted at the outset that in this author’s
opinion the aim of the automatic-parsing component
of a machine-translation...
... confirm the expression of prosemin
mRNA in some cell lines. A band of the predicted size
(500 bp) of the PCR product was observed for most of
the cell lines tested, including HPC-YO and HPC-YS,
in ... 31 000, indicating successful
digestion of the artificial trypsinogen pro-enzyme frag-
ment. The amount of 31 kDa prosemin increased in pro-
portion to the time of...
... critical role in the proliferation of
MH7A cells.
In order to determine whether MLN51 is involved
in the anti-apoptosis as well as cell proliferation of
MH7A in response to GM-CSF, we examined the
apoptosis ... angiogenesis in arthritic
joints [2–4]. Several cytokines and RA factors existing
in the RA environment stimulate the overgrowth of
FLSs, leading to the a...
... dopamine-
selective transporter is found.
Keywords: insect; neurotransmitter; transporter; dopamine;
octopamine; cocaine.
The catecholamine dopamine (DA), the phenolamine
octopamine (OA) and the indolamine ... does the moth OAT substitute for DAT in dopami-
nergic signaling pathways in the moth CNS, and what is the
nature of the mechanism that substitutes for OAT in the...
... (muscle). The application of the
ANOVA
technique allowed us to segregate the main
(intrinsic) activities of the respective elements from the
effects of their interactions. Using this approach, the
upstream ... sequences present in the respective constructs
are shown in the left portion of the figure as solid black lines. The upper line shows the linkage of...