Báo cáo khoa học: Meiosis and small ubiquitin-related modiﬁer (SUMO)conjugating enzyme, Ubc9 potx

... ARTICLE Meiosis and small ubiquitin-related modiﬁer (SUMO)-conjugating enzyme, Ubc9 Kengo Sakaguchi, Akiyo Koshiyama and Kazuki IwabataDepartment of Applied Biological Science, Faculty of Science and ... with CcUbc9, CcTopII and CcPCNA. Moreover, both TopII and PCNA homologs were known as Ubc9 interactors and the targets ofsumoylation. Immunocytochemistry demonstrates that CcUbc9, CcTopII and CcPCNA ... in meiosis. In C. cinereus, however, becauseCcPCNA and CcUbc9 exist together in meiotic nuclei,the interaction between CcPCNA and CcUbc9 and sumoylation may occur at a certain point of meiosis. ...

Báo cáo khoa học: "Jigs and Lures: Associating Web Queries with Structured Entities" potx

... Inter-national Conference on Acoustics, Speech and SignalProcessing, pages 181–184.[Kurland and Lee2004] O. Kurland and L. Lee. 2004.Corpus structure, language models, and ad-hoc infor-mation retrieval. ... discounting (Witten and Bell,1991), Jelinek-Mercer interpolation (Jelinek and Mercer, 1980), and Kneser-Ney (Kneser and Ney,1995).In the information retrieval community, Ponte and Croft (1998) ... 1.0050” hdtv 0.17 0.12 High Island Hammock/Stand Combosamsung plasma tv review 0 0.42 high island hammocks 1.00 1.0050” samsung plasma hdtv 0 0.35 hammocks and stands 0 0.10Table 3: Example...

Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf

... dimers, with mono-mers A and B in dimer 1 and C and D in dimer 2(Fig. 8). The a-crystallin domain of each monomer iscomposed of nine b-strands (labeled b2–b10), with theb6 strand situated in a large ... formationdepends upon contact of b-strand 10 from the C-ter-minal extensions of monomers A and D withb-strands 4 and 8 in the a-crystallin domain ofmonomers C and B, respectively (Fig. 8). A more ... monomer. Monomers A (green) and B(yellow) form dimer 1, while monomers C (red) and D (blue) form dimer 2. L5 ⁄ 7, the loop between b-strands 5 and 7 which containsb-strand 6; N term, amino terminus...

Báo cáo khoa học: Treatment with small interfering RNA affects the microRNA pathway and causes unspeciﬁc defects in zebraﬁsh embryos doc

... Treatment with small interfering RNA affects themicroRNA pathway and causes unspecific defectsin zebrafish embryosXiao-Feng Zhao, Anders Fjose, Natalia Larsen, Jon V. Helvik and Øyvind DrivenesDepartment ... efficiencies of different siRNAs and related RNA molecules in inducing MMB defects. asGFP, antisensestrand of GFP; dsGFP, double-stranded GFP without 3¢-overhangs;sGFP, sense strand of GFP.Embryos analyzed ... sequence. Single-stranded and double-stranded molecules without the characteristicfeatures of siRNA did not affect the level of miR-430b, as com-pared to non-injected (WT) and buffer-injected...

Báo cáo khoa học: Temperature and concentration-controlled dynamics of rhizobial small heat shock proteins doc

... evidence that complex size and chaper-one activity are linked. Mutations, and N- and C-terminaltruncations of B. japonicum class A and class B proteins,which led to smaller complexes, were accompanied ... temperature- and concentration-dependent dissociations were fully reversible.Complexes formed between sHsps and the model substratecitratesynthasewerestableandexceededthesizeofsHspoligomers. Small ... 2503Temperature and concentration-controlled dynamics of rhizobial small heat shock proteinsNicolas Lentze1, J. Andrew Aquilina2, Mareike Lindbauer1, Carol V. Robinson2 and Franz Narberhaus1,31Institut...

Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx

... Carbohydrate,glycolysisLactococcuslactisModeling Pi explicitly and regulationof pyruvate kinase (by Pi and FBP),PFK (by PEP) and GAPDH (byNADH) are critical to describeobservations (rapid increase in PEP,Pi and gradual decrease ... metaboliteconcentrations and metabolic ﬂuxes,both measured and nonmeasured. Ageneral parameter sensitivityanalysis is carried out to determine and characterize the parametershaving the most and least effectson ... lysineconcentration) were predicted and tested successfullyODE ss, sim,MCAMATLAB NG Time series of metabolitesmeasured by HPLC and enzyme assays; biomass and cell numbermeasured byspectrophotometryHua...

Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

... H4-K5, K8 and K12 acetylation [136–138]. In yeast, this group ismade up of NuA4 and Piccolo NuA4 which both uti-lize Esa1 as the HAT, and Esa1 was found to be essen-tial for H4-K5, K8 and K12 ... acetylation and deacetyla-tion, and transient recruitment of remodellers and transcription factors.A cycle of transcription commences with the recruit-ment of transcription factors and co-factors ... exist within CGislands which are characterized by their very high CGcontent and have an intrinsic resistance to DNA meth-ylation. CG-island promoters tend to be constitutively and ⁄ or ubiquitously...

Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx

... tumors and cell lines, miR-17-5p and miR-20a are induced in a manner that dependson cyclin D1 and repress the expression of cyclin D1.Hence, miR-17-5p ⁄ 20a and cyclin D1 form a feedbackloop and ... transcription factors E2F and Myc but,in turn, miR-17-92 downregulates the expression ofE2F and Myc [52]. In tumor progression, the tran-scription repressors ZEB1 and SIP1 and the miR-200family ... repressingthe indicated targets and presumably hundreds of other as yetunidentiﬁed targets. (B) miR-34a and the miR-34a-binding site inthe 3¢ UTR of genes shown in (A).miRNAs and cell signaling A. Ichimura...

Tài liệu Báo cáo khoa học: MicroRNAs and epigenetics doc

... cancer.DNMT 3A and 3BDNMTs 1, 3A, and 3B are key DNA methylationenzymes. Recent studies in human cells have demon-strated that PRC2 and DNMTs are physically and functionally linked [76], and that ... (Mathworks, Natick, MA,USA), we compared localization and strand directionbetween miRNAs and transcripts (Refseq genes and mRNAs). Intragenic and intergenic miRNAs were deﬁnedby whether the miRNAs ... an ATP-dependent manner [20]. Next, onestrand (the passenger strand) of the miRNA isremoved from the RLC, whereas the other strand (theguide strand) remains in the complex to form amature...

Tài liệu Báo cáo khoa học: MicroRNAs and cardiovascular diseases ppt

... disease and that,when miR-1 is overexpressed in normal and infractedrat hearts, this results in a slowed conduction velocity,excessively prolonged repolarization and the inductionof PVCs and ... arrhythmias. On the other hand, blockingmiR-1 function with antisense oligoribonucleotides wasfound to normalize the expression of Cx43 and Kir2.1,prevent QRS and QT prolongation, and reducearrhythmias ... proliferationboth in vitro and in vivo.Another study demonstrated that the angiotensin IItype 1 receptor (AT1R) and miR-155 are coexpressedin endothelial cells and VSMCs, and that miR-155translationally...

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