Báo cáo khoa học: Global shape and pH stability of ovorubin, an oligomeric protein from the eggs of Pomacea canaliculata pot
Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx
... courses and effects of unlabeled ligands and low pH on the dissociation rates of [125I]TC-PCSK9 (A) and [125I]TC-PCSK9-D374Y (B) from HepG2 cells. Binding to equilibrium and removal of unbound ... 4A). In the presence of a highconcentration of unlabeled wild-type PCSK9, the half-time of the rapid phase was reduced from 19 to 16 min and the half-time of the slow phase was reduced from 270 ... min. In the presence of unlabeled PCSK9-D374Y, the half-time of the rapid phase of [125I]TC-PCSK9-D374Y dissociation was reduced from 21 to19 min, and the half-time of the slow phase was...
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Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf
... membrane proteins (the hydropho-bic translocators) and one hydrophilic partner (alsocalled the V antigen in Pseudomonas aeruginosa and Yersinia spp.; Figs 1 and 2) comprise the translocon, and ... cell membrane, although the nature of the cellular signal required and the mecha-nism of its transduction are still a matter of debate[14,15]. The third, major part of the T3SS is the ‘translo-con’, ... rapidly and concurrently, and effectors are translocated in an ordered manner[16,17]. Translocon proteins presumably travel through the interior of the needle and, once having reached the outmost...
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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... expression of T-bet has beenseen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung tissue of mouse and spleen and thymus of human and mouse ... end of the gene, where the zebrafish and human sequences appearto be quite diverse. Together with the well-conservedgene organization, there is a conservation of syntenybetween the human and ... be very simi-lar to their human homologues. Both the human and zebrafish T-bet and Foxp3 genes contained the samenumber of exons and introns. t-bet contained six exons and five introns, whereas...
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Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx
... according to the manufacturer’s instruction.Statistics The data are presented as means ± standard errors of the mean (SEMs), and were statistically analyzed by means of the unpaired t-test or the Welch ... musclewith organ, but without fat, of WT and H-PGDS TG mice (n = 6). Continuousdissections of mouse fat and bone in the whole body were quantified by use of amicro-CT scanner and LATHETA software(Aloka). ... mem-brane, and hybridized with the 32P-labeledfull-length cDNA for human H-PGDS. (C)Immunohistochemical analysis of transgeneexpression in the liver and WAT. Paraffinsections of liver and WAT from...
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Tài liệu Báo cáo khoa học: Neuropeptide Y and osteoblast differentiation – the balance between the neuro-osteogenic network and local control ppt
... Y5 and y6) thatvary in their binding profiles and in their distributionin the central nervous system and periphery. Y1, Y2 and Y5 are the best characterized NPY receptors, and the majority of ... stromal cells and osteoblasts [40,46–48],despite the absence of the other Y receptors (Y2, Y4,Y5 and y6) [40,46]. In addition to the presence of NPY-immunoreactive fibers and the presence of NPY receptors, ... turnover,namely Y2 and leptin [51,52]. Another seminal findingthat came from the analysis of these animal modelswas that the actions of the NPY system in bonebiology are more complex than simple downstreammediation...
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Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase–methionine synthase reductase complex docx
... absorptionspectrum of the purified enzyme was typical of the hydroxycobalamin form of the enzyme (Fig. 2). The recovery of the activity was 10%, and the enzymewas purified 3669-fold. The specific activity and ... addition of the FMN domain of MSR alongwith AqCbl and MeCbl caused a 6-fold and 20-foldstimulation of hMS activity. The presence of NADPHin the preincubation mixture along with MSR and MeCbl ... min at 37 °C, and quenched and analysed following the protocol for the radioactive hMS activity assay. The concentration of MSR and the FMN domain were determined by the absorbancevalue at 450...
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Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulfide isomerase family proteins with nonclassic active center motifs pdf
... Expression of GmPDIL-3a and GmPDIL-3b in soybeantissues. (A) Purified recombinant GmPDIL-3a (lanes 1 and 4),GmPDIL-3b (lanes 2 and 5) and proteins extracted from the cotyle-don (lane 3) were analyzed ... JapanIntroductionSecretory, organelle and membrane proteins are synthe-sized and folded with the assistance of molecular chap-erones and other folding factors in the endoplasmicreticulum (ER). In many cases, the process ... of GmPDIL-3a, GmPDIL-3b and orthologs of otherplants.Fig. S3. Expression and CD analysis of recombinantGmPDIL-3a and GmPDIL-3b.Table S1. List of primers for ATG-mutagenesis of GmPDIL-3a and...
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Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt
... elevated, and consequently, the levels of nuclear SREBP-1c protein and lipogenesisare enhanced in the liver and adipose tissues. Intake of energy molecules such as sugars, carbohydrates and saturated ... apparatus, where the site 1 and site 2 proteases cleave the SREBPs [3,4].Upon restoration of cellular cholesterol, Insig, anotherkey regulator of ER membrane proteins, traps and retains the SREBP–SCAP ... desaturase; GPAT, glycerolphosphate acyltransferase; DGAT, diacyl-glycerol acyltransferase; 6PG, 6-phosphoglu-conate.H. Shimano Physiology and pathophysiology of the SREBP familyFEBS Journal...
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Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins pptx
... dinophysistoxins and ana-logs) affect Ser ⁄ Thr protein phosphatases and theireffects on cell adhesion and cytoskeletal dynamics, the disruption of which is linked to loss of cell polarity, and ... promoter and the biological significance of Ser ⁄ Thr and Tyr protein phosphatases have beenextensively investigated in cancer-related research. The hyperphosphorylation of IFs is one of the earlybiochemical ... being the most studied of these. IFsmaintain cell shape and the structural integrity of cellcontents, and provide protection against various types of stress. The mechanism of action of OA as a potenttumor...
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Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: a new view of palytoxin toxicity ppt
... Ca2+into the cellsbecause of the intracellular Na+influx and membranedepolarization; and (c) an as yet unidentified pathwaythat is independent of changes in membrane potentialor changes in pH [9]. The ... spectrin, actin and ankyrin [48,49], and even regulation of Na+pumpactivity might depend on its linkage to the actin filamentsystem [50,51]. In any case, the study of the possibleexistence of some ... recently these dinoflagellates have also started to appearin the Mediterranean Sea. Two of the most remarkable properties of paly-toxin are the large and complex structure (with different analogs,...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếThơ nôm tứ tuyệt trào phúng hồ xuân hươngTăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘITÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ