Báo cáo khoa học: Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells pptx

Báo cáo khoa học: Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells pptx

Báo cáo khoa học: Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells pptx

... Journal compilation ª 2008 FEBS Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells Min-Jung Kim 1 , Kee-Ho Lee 2 and ... targets for cancer treatment. Results To examine the kinetics of the apoptotic cell death induced by ionizing radiation in human c...
Ngày tải lên : 07/03/2014, 05:20
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Báo cáo khoa học: Gc recruitment system incorporating a novel signal amplification circuit to screen transient protein-protein interactions pot

Báo cáo khoa học: Gc recruitment system incorporating a novel signal amplification circuit to screen transient protein-protein interactions pot

... and it therefore allows for cellular changes in the mating pro- cess. Therefore, the generation of diploid cells with opposite mating-type cells can be used to screen interacting protein pairs, ... with intact a cells. The formation of diploid cells in medium lacking methionine and lysine depends on the affinities of the protein pairs [12]. To verify our hypothesis that the...
Ngày tải lên : 05/03/2014, 23:20
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Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... (solvent B) at a flow rate of 0.3 mLÆmin )1 : lin- ear increase from 0% B to 50% within 20 min followed by a linear increase to 95% B in 5 min, holding B for an additional 5 min. This gradient was ... 673 Determination of amino acid connectivity via partial hydrolysis of erythrochelin Three milligrams of erythrochelin were partially hydrolyzed in 200 lLof6m HCl at 110 °C for 20...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

... more in WAT of TG mice than in WAT of WT mice. Serum levels of triglyceride, glucose, leptin and insulin, and insulin sensitivity, in TG mice After 6 weeks of normal or HF diet, serum levels of triglyceride, ... regulation of insulin produc- tion in pancreatic islet cells [39–41]. Thus, the increased insulin level seen in H-PGDS TG mice when on the HF diet might be due...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc

... be a sink for Cu(I). This could be sufficient for a redox-silencing role of MT3 for Cu. In this context it might be interesting to search for possible binding partners of Cu(I) 4 MT3. Since the ... occurred in the Zn cluster [32]. Indeed, exposure of Cu(I) 4 - Zn 4 MT3 to air resulted in the slow formation of a disulfide linkage by cysteine oxidation of the a-domain and...
Ngày tải lên : 16/02/2014, 15:20
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Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

... were determined by SDS-PAGE followed by silver staining. Preparation of mouse activated protein C Incubation of mouse protein C with human or bovine thrombin using conditions known to work well for human protein ... randomized. No binding was detected in buffer lacking Ca 2+ for any of the proteins tested. Protein binding equilibrium data (R eq ) were fitted to a one- site bind...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt

Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt

... interface [8,9]. BTB ⁄ POZ proteins are often transcriptional regulators containing a C 2 H 2 domain for DNA binding, but can also be found in combination with various other protein–protein inter- action ... proteins use their BTB ⁄ POZ domain to interact with the cullins CUL3A and CUL3B [3,4,16], we inves- tigated what kind of protein–protein interactions were facilitated by their MATH...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: The yeast ubiquitin ligase Rsp5 downregulates the alpha subunit of nascent polypeptide-associated complex Egd2 under stress conditions docx

Tài liệu Báo cáo khoa học: The yeast ubiquitin ligase Rsp5 downregulates the alpha subunit of nascent polypeptide-associated complex Egd2 under stress conditions docx

... or mis-folding of proteins may also be a signal for ubiqui- tination of denatured proteins that are recognized by the appropriate ubiquitin ligase. In human cells, block- ing of the metabolism of mis-folded ... the stability of Egd2 was decreased in wild-type cells but not in rsp5 mutant cells in the absence of CX (Fig. 2A). However, in the pres- ence of CX, E...
Ngày tải lên : 18/02/2014, 11:20
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Tài liệu Báo cáo khoa học: TransLISA, a novel quantitative, nonradioactive assay for transcription factor DNA-binding analyses pdf

Tài liệu Báo cáo khoa học: TransLISA, a novel quantitative, nonradioactive assay for transcription factor DNA-binding analyses pdf

... 8.4-fold induction of HSF1 DNA-binding in heat-shocked HeLa cells, and, on average, 25.8-fold induction of HSF1 DNA-binding in heat-shocked MEFs when compared to the untreated cells. The results are well in line ... through the DNA-binding domain. Stable binding requires simultaneous binding of all DNA-binding domains in a trimer to three adjacent nGAAn repeats. Therefore, a f...
Ngày tải lên : 18/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Hypoxic resistance to articular chondrocyte apoptosis – a possible mechanism of maintaining homeostasis of normal articular cartilage pdf

Tài liệu Báo cáo khoa học: Hypoxic resistance to articular chondrocyte apoptosis – a possible mechanism of maintaining homeostasis of normal articular cartilage pdf

... role in intracellular signalling and thus in cell physiology and cellular destruction. ROS are known to induce a wide range of responses, depending on cell type and levels of ROS within the cell ... 2¢,7¢-dichlorodihydrofluorescein diacetate; DR-5, death receptor-5; JC-1, 5,5¢,6,6¢-tetrachloro- 1,1¢3,3¢-tetraethylbenzimidazol-carbocyanine iodide; JNK, c-Jun N-terminal kina...
Ngày tải lên : 18/02/2014, 14:20
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