... in the vicinity of the steadystate. We do this to investigate the stability of this state. In this way we obtain the in uence a small change in the concentration of substance j, i.e. Dxj,hasonthetimedisplacement ... (IMC, VUA) and Mathematical Biochemistry (SILS, UvA),Amsterdam, the Netherlands;3Department of Biochemistry and Molecular Biology, Faculty of Chemistry and CeRQT at BarcelonaScientific Parc, ... (negative) in uence a substrate has on its own removal. It is obtained for allsubstrates of any elementary reaction. The main point of the present section is that any Jacobianmatrix element equals the...