Báo cáo khoa học: Study of synthetic peptides derived from the PKI55 ppt

Báo cáo khoa học: Study of synthetic peptides derived from the PKI55 ppt

Báo cáo khoa học: Study of synthetic peptides derived from the PKI55 ppt

... b 2 isoforms [13]. The present study aimed to identify peptides derived from the amino acid sequence of the PKI55 protein to be used as pharmacological tools. The effects of the peptides in vitro ... peptides. The level of PKC a, b 1 , b 2 and f isoforms was also studied. Results Synthesis of peptides derived from PKI55 and their inhibitory effect on r...
Ngày tải lên : 07/03/2014, 05:20
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Báo cáo khoa học: Interaction of synthetic peptides corresponding to hepatitis G virus (HGV/GBV-C) E2 structural protein with phospholipid vesicles doc

Báo cáo khoa học: Interaction of synthetic peptides corresponding to hepatitis G virus (HGV/GBV-C) E2 structural protein with phospholipid vesicles doc

... vesicles, as the blue shift of Trp was 11 nm. To study the contribution of electrostatic inter- actions to the binding of both peptides with negatively charged SUVs, titration of the peptides with ... nm, expressed as the percentage of the fluorescence of the lipid-free peptides vs. the added lipid concentration. The data were analysed using Graphpad softw...
Ngày tải lên : 07/03/2014, 17:20
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Báo cáo khoa học: Characterization of a prokaryotic haemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath) ppt

Báo cáo khoa học: Characterization of a prokaryotic haemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath) ppt

... 2433 C-terminal end of helix III, pointing towards the inside of the bundle, and Cys128 was located to the random coil of the C-terminal end of the protein (C-terminal to helix IV) (not shown). The long ... members of the haemerythrin family and it is located in the central region of these proteins. We therefore named the MCA0715-encoded protein Methylococcus cap...
Ngày tải lên : 07/03/2014, 17:20
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Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx

Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx

... cell–cell adhesion complex and required for the for- mation of epithelia in the embryo and the maintenance of the polarized epithelial structure in the adult [2]. As a single-span transmembrane-domain ... suppressed the disruption of cell–cell adhesion, the scattered phenotype of the cells and the redistribution of E-cadherin into the cytoplasm (Fig. 5C). C ab c...
Ngày tải lên : 19/02/2014, 05:20
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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx

Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx

... independent of the thermodynamic and kinetic properties of the binding process and is solely based on the detectability of the peptides of interest. We have used this method to show that binding of fosfomycin ... function of temperature [13]. The heat capacity change (DC p ) was obtained from the slope of Kirchoff’s plots (DH vs. T). Analysis of the experimen...
Ngày tải lên : 19/02/2014, 13:20
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Tài liệu Báo cáo khoa học: "Order of Subject and Predicate in Scientific Russia" pptx

Tài liệu Báo cáo khoa học: "Order of Subject and Predicate in Scientific Russia" pptx

... his system of mechanical translation of Russian upon word-for-word translation, strip- ping the Russian words of their endings to identify them by their stems, which are listed in the dictionary. ... twenty-eight pages of continuous text 2 were analyzed for the relative positions of the subject and the predicate. The predicate spot was determined syntactically, b...
Ngày tải lên : 19/02/2014, 19:20
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Tài liệu Báo cáo khoa học: Transcription of individual tRNA1Gly genes from within a multigene family is regulated by transcription factor TFIIIB pdf

Tài liệu Báo cáo khoa học: Transcription of individual tRNA1Gly genes from within a multigene family is regulated by transcription factor TFIIIB pdf

... through the TBP component with the AT-rich elements but the complexes were readily disso- ciated in the absence of TFIIIC. The TATA sequences present elsewhere in the flanking regions of these genes could ... to the differences in their tran- scription levels, the dissociation of TFIIIB complexes in the presence of heparin was examined. Because hep- arin strips off t...
Ngày tải lên : 20/02/2014, 02:21
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Tài liệu Báo cáo khoa học: Characterization of ICAM-4 binding to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins pptx

Tài liệu Báo cáo khoa học: Characterization of ICAM-4 binding to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins pptx

... contrast to the CD11b I domain GST, the majority of the CD11a I domain GST was found in the insoluble fraction of the E. coli lyzate. Modification of the solubilization conditions and increasing the volumes of ... providing the LLG-C4-GST protein. These studies were supported by the University of Helsinki, the Academy of Finland, the Sigrid Juse ´ lius Foundat...
Ngày tải lên : 20/02/2014, 11:20
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Báo cáo khoa học: A novel metallocarboxypeptidase-like enzyme from the marine annelid Sabellastarte magnifica – a step into the invertebrate world of proteases pdf

Báo cáo khoa học: A novel metallocarboxypeptidase-like enzyme from the marine annelid Sabellastarte magnifica – a step into the invertebrate world of proteases pdf

... enzyme, the target of the present study, did not appear at around 34 kDa, which is the mass assigned to it as a potential MCP (see MALDI-TOF MS analysis and below), when the extracts (either from the ... with the aim of both perturb- ing the MS spectrum and capturing the MCP in the body extract. The control spectra, as well as the ‘per- turbed’ one (by rPCI addit...
Ngày tải lên : 07/03/2014, 02:20
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt

Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt

... strongly depends on the nature of the acyl moiety [9,10]. The fine tuning between these two features is of consider- able importance for the development of selective potent drugs. The biosynthesis of the peptide ... has been shown that the activity of these acidic lipopeptides is significantly influenced by the length and structure of their fatty acid moieties [9,10]....
Ngày tải lên : 07/03/2014, 04:20
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