... samples in vivo and in vitro. We also describe the use of NMR
spectroscopy to determine the binding mode of new low molecular
mass inhibitors of the West Nile virus NS2B–NS3 protease which were
discovered ... The Authors Journal compilation ª 2009 FEBS 4255
NMR study of complexes between low molecular mass
inhibitors and the West Ni...
... polysaccharides degraded and
of the sugars solubilized should aid in the understand-
ing of the action of the cellulolytic system and in the
evaluation of its efficiency in the degradation process.
We ... those
observed at the given times. The concentrations of the
metabolites were calculated from the quantification of
the signals in the
1
H NMR spectra...
... features produces the best results.
A subsequent innovation was the detection and
removal of the objective parts of documents and
the application of a polarity classifier on the rest
(Pang and Lee, 2004). ... max
t
(tf) is the maximum frequency of any
term in the document and avg dl is the average
number of terms in all the documents. For ease of
reference...
... average co-ordinates (the blue colour denotes the side chains of Arg2, Tyr4, Ile5, His6 and the yellow the side chains of Val3
and Pro7) (a) with the the X-ray structure of AII in the Fab131–AII complex ... 2003
On the molecular basis of the recognition of angiotensin II (AII)
NMR structure of AII in solution compared with the X-ray structure of AII boun...
... polymorphism of monomeric subunit c is
due to the interaction of the monomer with the artificial
environment lacking the stabilizing protein/protein contacts
within the ring. The undecameric c ring of the ... table,
and resist boiling in SDS for 5 min in the case of the
undecameric c ring of P. modestum [41]. This stability of the
ring makes structural flexibil...
... sentences.
In another study, Whittemore, Ferrara, and
Brunner (1989) quantify the occurrence of PPs in
the 13 dialogues in terms of the syntactic types to
which they attach and the overall syntactic ...
b. the size of the hotel
The algorithm for the other group is:
Check to see if preceding lowest consti-
tuent
is a definite NP and part of a
partitive ex...
... study of microRNAs in silico and in vivo: diagnostic and
therapeutic applications in cancer
Scott A. Waldman
1
and Andre Terzic
2
1 Departments of Pharmacology and Experimental Therapeutics and ... leukemia cells [31]. Indeed,
there is a reciprocal relationship between the expres-
sion of miR-15a and miR-16-1 and of Bcl-2, and the
heterologous production of t...
... and
cloned between the cytomegalovirus (CMV) promoter
and the start codon of the Gaussia luciferase gene
of the optical reporter gene vector (Fig. 1C). The
Bioimaging of miRNA biogenesis and regulation ... pre-miRNA by Dicer. The synthetic duplex form of pre-
miRNAs carrying quencher and organic dye at each strand can be designed. In the presence of the Dic...
... esti-
mation of the bandwidth and the intensity of the bands
making up the amide I or I¢ region. Thereafter, curve fitting
was performed and the heights, widths and positions of
each band were optimized ... this study we used IR spectroscopy to study the
secondary structure of the catalytic domain of PKCf
and the effect of its substrate, MgATP, and als...
... together,
these results suggest that the DNA-binding step corres-
ponding to phase I accounts for the formation of non-
specific complexes and that, at the beginning of
phase II, the majority of complexes ... product. The stability of
IN during the time-course of the reaction and the
influence of protein aggregation are discussed.
Results
General features of...