Báo cáo khoa học: Activator-binding domains of the SWI ⁄ SNF chromatin remodeling complex characterized in vitro are required for its recruitment to promoters in vivo pot

... affecting the SWI ⁄ SNF complex caused reduced activation of these genes within the same time window. The activator-binding domains in the Swi1 and Snf5 subunits of the SWI ⁄ SNF complex are essential ... activation domains and the activator-binding domains of Swi1 and Snf5 of the yeast SWI ⁄ SNF chromatin remodeling complex has previously been characterized in vitro. Although deletion of both activator-binding ... with these activator-binding domains isthus critical for normal galactose induction of the tested genes. Interestingly, the strains lacking either the Fig. 3. The activator-binding domains of the...

Báo cáo khoa học: Functional domains of the human epididymal protease inhibitor, eppin docx

... tris-tricine gels depending upon whetherthey are pre-incubated in dithithreitol, or not(Fig. 1H).Protease inhibition activity of eppin and its domains Eppin and the two domains were compared for theirability ... wereexposed to the two domains of eppin in solutiontogether, survival again dropped to approximately20%. This suggests that the individual domains of eppin, when exposed to each other in solution, ... cellmembrane remains to be discovered. The resultsobtained in the present study are interesting becausethey indicate that both domains are capable of causingrespiratory uncoupling.These data suggest...

Tài liệu Báo cáo khoa học: Functional dissection of the Schizosaccharomyces pombe Holliday junction resolvase Ydc2: in vivo role in mitochondrial DNA maintenance pptx

... the correctpositioning of the SAP motifs in relation to the rest of the protein as well as for the stability of the protein. The truncated Ydc2 mutant proteins localize to the mitochondria in S. ... triple-helixmotif was required to hold the junction in a square-planarconformation, it was interesting to test whether RuvAbinding to the junction could substitute for the function of the protruding bundles, ... residues that map to the structural core shared with RuvC including the catalyticsite, could be due to a defect in binding to the Hollidayjunction. To investigate the interactions of the truncatedYdc2...

Báo cáo khoa học: Identiﬁcation of the amniotic ﬂuid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx

... expression of the insulin-like growthfactor-I-binding protein-1 (IGFBP-1) phosphoisoform in pre-eclamptic Wharton’s jelly and its role in the regulation of collagen biosynthesis. Clin Chem Lab ... Cellular actions of the insulin growth factor binding proteins. Endocr Rev 23,824–854.3 Baxter RC (2000) Insulin-like growth factor (IGF-)binding proteins: interactions with IGFs and intrinsicbioactivities. ... composed of  65 aminoacids connecting the N- and the C-terminal domains. The prevalent phosphoacceptor sites of the monopho-sphorylated protein are located in a PEST region pres-ent in proteins...

Báo cáo khoa học: Crystal structure of the halotolerant c-glutamyltranspeptidase from Bacillus subtilis in complex with glutamate reveals a unique architecture of the solvent-exposed catalytic pocket docx

... littlecorrespondence in the amino acids that are involved in the recognition of the functional groups of the ligands.Moreover, in GGT the a-carboxyl group of the gluta-mate protrudes into the groove, whereas in ... present in most other GGTs at the C-terminal region of the L-subunit. In E. coli GGT, upon autocatalytic cleavage of the peptide bond on the N-terminal side of Thr391, the C-terminal segment of the ... mostly of high quality and continuous, the densi-ties for the N-terminal His-tag segment and resi-dues 396–402, corresponding to the C-terminus of the L-subunit, were poorly deﬁned; therefore, these...

Báo cáo khoa học: Respective roles of the catalytic domains and C-terminal tail peptides in the oligomerization and secretory trafﬁcking of human acetylcholinesterase and butyrylcholinesterase potx

... suppres-sion of the cysteine.Thus, it appears that the effect of a C-terminalcysteine on the trafﬁcking of cholinesterase in the secretory pathway largely depends on the nature of the preceding catalytic ... subunits [37]. This indicates apredominant in uence of the catalytic domain onoligomerization.Role of the C-terminal cysteineMutation of the cysteine located at )4 from the C-ter-minus to ... The patterns of oligomers were similar for Aa and Ab, as well as for Ba and Bb, indicat-ing a predominant in uence of the catalytic domains. However, addition of a cysteine within the aromatic-rich...

Báo cáo khoa học: Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops docx

... orientations in the membrane; the N terminus of the N-terminal domainis extracellular, while the N terminus of the C-terminaldomain is intracellular. In the [st326]2HCT family,TMS I is not part of the ... asobserved for the percentage of hits between the N-terminal domains or the C-terminal domains alone. The results strongly suggest that the N- andC-terminal halves of the ST3 sequences sharesequence ... membrane topology. The structure of the domains is related by a pseudotwofold symmetry axis perpendicular to the plane of the membrane. The substrate is bound in a pore in between the two domains in...

Báo cáo khoa học: Solution structure of the bb¢ domains of human protein disulﬁde isomerase docx

... better the contribution of the b¢ binding site to PDI activity, the inhibitory in uenceon the refolding of RNase A caused by the peptidesbinding b¢ was examined. In the assay, incubation of unfolded ... domainincreased the Km to 30 lm, and loss of an additional cys-teine in the a domain resulted in an increase of the Km to 50 lm [25,27]. On the other hand, the role of the bdomain seems to ... concerninghow they bind unfolded proteins [20–22].Residue-speciﬁc interactions The importance of individual amino acids in humanPDI for the binding of D-somatostatin was previouslyinvestigated...

Báo cáo khóa học: Structural characterization of the human Nogo-A functional domains Solution structure of Nogo-40, a Nogo-66 receptor antagonist enhancing injured spinal cord regeneration ppt

... lycophosphatidylinositol-linked NgR, via its leucine-rich r epeat containing do main. The binding of Nogo-66 to N gR is competitively inhibited by a peptideconsisting of the N-terminal 40 residues of Nogo-66,named ... be induced to form a helical structure via interaction w ith Zn2+.Furthermore, the d etermination of the Nogo-40 solutionstructure offers a starting point for further understanding the interaction ... development of therapeutic agents for treating spinalcord injury. Nogo-A, the largest member of the Nogo fam-ily, is a multido main protein containing at le ast two regionsresponsible for inhibiting...

Báo cáo khoa học: Biochemical analysis of the human EVL domains in homologous recombination doc

... [15–18]. Theseactin-binding activities are conserved in the EVH2domain [19,20]. On the other hand, the EVH1 domainbinds to proteins containing the consensus sequenceD ⁄ E FPPPPXD ⁄ E [21–23]. The ... clarify the contributions of these proteins in the HRR pathway.During the cytoplasmic actin -remodeling process, the ENA ⁄ VASP family proteins bind to both the barbed end and sides of actin ﬁlaments ... domain alsobinds to proﬁlin and proteins containing the SH3 andWW domains [17,24–26]. These facts suggest that the EVH1, Pro-rich and EVH2 domains all have the potential to function in protein...

Xem thêm

Từ khóa: báo cáo khoa học ảnh hưởng của việc thay thế cỏ xanh trong khẩu phần bằng bã dứa ủ chua đến khả năng sản xuất của bò thịt pot tài liệu báo cáo khoa học bản chất của khủng hoảng kinh tế thế giới pdf lam the nao de tom tat bao cáo khoa hoc báo cáo khoa học báo cáo khoa học mẫu báo cáo khoa học y học Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoại Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN Phát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninh Nghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùng Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chế Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúng Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tin Thơ nôm tứ tuyệt trào phúng hồ xuân hương Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIX Tổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2 Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật chuong 1 tong quan quan tri rui ro Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP