Báo cáo khoa học: Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria doc
... compilation ª 2009 FEBS 6713
Assembly of nuclear DNA-encoded subunits into
mitochondrial complex IV, and their preferential
integration into supercomplex forms in patient
mitochondria
Michael Lazarou
1
, ... imported complex IV subunits can integrate into
complex IV and its supercomplexes by associating with
pre-existing subunits and integra...
... the ER extract of
PSG cells of a normal-level fibroin-producing silkworm
Table 2. Determination of molar ratios of H-chain, L-chain, and fhx/P25 in the fibroin secreted into cocoons of a normal breed ... glycoprotein [28,29], in uenza
virus hemagglutinin [30,31], and IgM [32] in ER, a further
role of N-linked oligosacharide chains of fhx/P25 in the
process of assem...
... acid and docosahexaenoic
acid, which are found in fish oil, downregulate LPS-
induced NF-jB DNA binding and p65–NF-jB
expression, and increase IjBa expression and doco-
sahexaenoic acid and ⁄ ... (Fig. 2).
Effects of CRLPs on cytokine and chemokine
secretion and mRNA expression in macrophages
We initially examined the effects of CRLPs on the
release of TNFa, IL-6, IL-1b...
... pS2 gene. In the initial experiments the increase
of acetylation of histone H3 and H4 at ER-regulated
cathepsin D and pS2 promoters was observed within
10 min of estrogen treatment, peaking at 1 ... (5-aza-2¢-deoxycyti-
dine, 5Aza-dC) results in a loss of methylation, loss of
BRM and MeCP2 binding and reactivation of tran-
scription [174]. In cancer cells, changes i...
... FIH binding
To understand the interplay between HIF-1a, FIH,
and IjBa, we coexpressed these proteins in HEK293
cells and examined protein interactions by performing
immunoprecipitation and immunoblotting ... interactions with ASB4 and Notch-1. By using yeast
two-hybrid screening, Ratcliffe et al. identified two
ARD-containing proteins, p105 and uveal autoantigen
with coiled-coil do...
... using pepsin. Pepsin cleaves
in the telopeptide domains of type II collagen and in the
noncollagenous domains of the minor collagens, type XI
and IX, but leaves their triple helical domains intact. ... to interfere with the interactions needed to form
cross-links and mature them into trivalent pyridinoline
residues. In addition, using antibodies that recognize specific
cros...
... have indi-
cated that the CagA
PY
-induced cell elongation pheno-
type also involves tyrosine dephosphorylation of
cortactin, vinculin and ezrin, which are three well-
known actin-binding proteins ... the amount of intracellu-
lar CagA
PY
. Cortactin, ezrin and vinculin are all Src
substrates, and Src inactivation causes dephosphoryla-
tion of these proteins and is crucial for t...
... pheromones
to elicit a mating response in cells of the opposite
mating type. Cdc42 is involved in pheromone signal-
ling that eventually results in G
1
arrest and the for-
mation of a mating projection ... formation of a mating
projection [28]. Furthermore, homologues of oxysterol-
binding proteins, a family of proteins that regulate
the synthesis and transport of sterol...
... sulfo-
bromophthalein to rat and human ligandins: characteri-
zation of a binding-site peptide. Biochim Biophys Acta
955, 296–300.
52 Gregus Z & Klaassen CD (1982) Role of ligandin as a
binding protein and ... anthocyanin sequestration, is a flavonoid-
binding protein. Plant Physiol 123, 1561–1570.
24 Grotewold E (2004) The challenges of moving chemicals
within and out of cel...
... Analysis of two CBP
(cAMP-response-element-binding protein-binding
protein) interacting sites in GRIP1 (glucocorticoid
receptor-interacting protein), and their importance for
the function of GRIP1. ... conserved AF-2 domain of
NRs [22]. The C-terminal region of the p160 co-activa-
tor can interact with the AF-1 domain of some NRs
and enhance their AF-1 activities in the...