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Learning Patient-Specific Cancer Survival Distributions as a Sequence of Dependent Regressors docx

Learning Patient-Specific Cancer Survival Distributions as a Sequence of Dependent Regressors docx

Learning Patient-Specific Cancer Survival Distributions as a Sequence of Dependent Regressors docx

... median survival time, e.g., a doctor can tell a specific patient with earlystage lung cancer that s/he has a 50% 5-year survival rate.In general, today’s cancer survival rates and median survival ... Such datasets are considered censored. Survival analysis provides many tools for modeling the survival time T of a population, such as a group of stage-3 lung cancer patients. A basic quantity of ... the same set of 25 features. As a baseline for this cancer registry dataset, we alsoprovide a prediction based on the median survival time and survival probabilities of the subgroup of patients...
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Tài liệu Báo cáo Y học: Use of site-specific recombination as a probe of nucleoprotein complex formation in chromatin Micha Schwikardi and Peter Droge ¨ potx

Tài liệu Báo cáo Y học: Use of site-specific recombination as a probe of nucleoprotein complex formation in chromatin Micha Schwikardi and Peter Droge ¨ potx

... bp was impaired. This impediment wasmaintained over at least 72 h and was not affected by thetranscriptional status of chromatin nor by inhibitors of histonedeacetylases and topoisomerases. ... recombination on episomaland on genomic targets, we have shown that the dynamicnature of chromatin renders a site of at least 34 bp in generalreactive for recombination. However, the assembly of and/or ... gd124NLS.Recombination is not affected by inhibitors of histonedeacetylases or topoisomerasesHistone modifications such as acetylation and phosphoryl-ation play important roles in the regulation of chromatinstructure....
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Báo cáo khoa học: A novel, promoter-based, target-specific assay identifies 2-deoxy-D-glucose as an inhibitor of globotriaosylceramide biosynthesis docx

Báo cáo khoa học: A novel, promoter-based, target-specific assay identifies 2-deoxy-D-glucose as an inhibitor of globotriaosylceramide biosynthesis docx

... synthase gene; Gb4, globotetraosylceramide (GalNAcb1,3Gala1,4LacCer); GD 1a, NeuAca2,3Galb1,3GalNAcb1,4(NeuAca2,3)LacCer; GD1b, Galb1,3GalNAcb1,4(NeuAca2,8NeuAca2,3)LacCer; GM1, Galb1,3GalNAcb1,4(NeuAca2,3)LacCer; ... Fan JQ, Ishii S, Asano N & Suzuki Y (1999) Acceler-ated transport and maturation of lysosomalalpha-galactosidase A in Fabry lymphoblasts by anenzyme inhibitor. Nat Med 5, 112–115.29 Mattocks ... relative luciferaseactivity as a percentage of the luciferaseactivity of untreated cells. Error bars,mean ± SD, n = 2. (B) Time -dependent alteration of luciferase activity of HML-Gb3cells after...
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Reading Theory as a Microcosm of the Four Skills

Reading Theory as a Microcosm of the Four Skills

... in their emphasis. It is my belief that in giving the L2 student both as much input and practice as they can reasonably manage, and a strong metalinguistic awareness, we, as teachers give the ... Ireland and Britain.One of the most important initial tasks for any teacher is the task of knowing his clients. The notion of needs analysis is absolutely central. Even with as few details as ... only taught as a means to accessing literature, be it classical, technical or otherwise. Any of the group that actually work, will almost certainly be trying to improve their English, as a means...
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Social Phobia as a Consequence of Brain Defects

Social Phobia as a Consequence of Brain Defects

... This type of medication is used occasionally as ananxiolytic; however olanzapine is primarily used as an anti-psychotic.IV. Suppressants of neural excitability that regulate gabaergictransmission: a. ... specificphysical signs with imbalances in autonomic neurotransmission. In thisformulation, the physical complaints typical of social phobia, areassociated with rapid release of catecholamines (noradrenaline, ... Martis, Macklin, Lasko,Cavanagh, Krangel, Orr, Pitman, Whalen, & Rauch, 2005; Liberzon& Phan, 2003). This, if anything, suggests that amygdala hyperactivityis a common thread of fear...
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Social Phobia as a Consequence of Cognitive Biases

Social Phobia as a Consequence of Cognitive Biases

... data are subsequently treated as if originating in a scale of equal intervals. This violates the basic postulates of the analysis of variance. The relevant data should have been properly treatedthrough ... observer. Again, itis difficult to grasp the meaningfulness of this finding, let alone as evidence of a bias. However that may be, this putative ‘‘bias’’ is assigned a role of some importance as it ... mundane events. A former military officer describes an oralexamination at university as worse than going into battle. A landscapedesigner is convinced that an unsteady grip on a cup of coffee...
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Social Phobia as a Consequence of Inadequate Social Skills

Social Phobia as a Consequence of Inadequate Social Skills

... counterparts.Are Social Skills Deficits Characteristic of a Subtype of SocialPhobia? Are social skills deficits typical of a certain subtype of socialphobia, rather than social phobia as such? ... socialskills has been assessed in research.Assessment of Social Skills of Social Phobic Individuals As the assessment of social skills had to be fashioned out of the concep-tual imprecision of ... or altogether undesirable. As a manner of speaking, social phobia might be typified by what such individuals failto do (e.g. take a stand, initiate, take charge) and achieve socially(e.g. associates,...
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Social Phobia as a Consequence of Individual History

Social Phobia as a Consequence of Individual History

... assessment of classroom (shy, anxious) behavior bythe teacher as well as peer assessment of social behavior (popularity,aggression, and isolation) at school.At the age of 8 no association was found ... Construct of ‘‘Behavioral Inhibition’’ A longitudinal study of social anxiety, although not making use of themodern category of social phobia as it was carried out between 1929 and1959 (Kagan & ... behavior of the socially phobicchildren either as exhibiting an exacerbation of normal social anxietyand behavior or as being qualitatively apart.Second, how does social phobia relate to avoidant...
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