... Rev Panam Salud Publica/Pan Am J Public Health 25(4), 2009Impact of chronic disease on quality of life among the elderly in the state of São Paulo,Brazil: a population-based study Margareth ... Original researchLima MG, Barros MBA, César CLG, Goldbaum M, Carandina L, Ciconelli RM. Impact of chronic dis-ease on quality of life among the elderly in the state of São Paulo, Brazil: a population-based ... (ISA-SP)). Sample population The following areas were included in the ISA-SP: the cities of Botucatu and Campinas; an area encompassing the cities of Itapecerica da Serra, Embu, and Taboão da...