... the base-line for analyzing potential granule-sorting domains.Attachment of the entire 228 amino acid C-terminaltail of PC5 ⁄ 6A to the Fc fusion protein causes a signi-ficant increase in its ... receptor, isanchored to secretory granules via a C-terminal trans-membrane insertion. Biochemistry 41, 52–60.14 Garcia AL, Han SK, Janssen WG, Khaing ZZ, Ito T,Glucksman MJ, Benson DL & Salton ... domains in the context of the native proteins. a- Helical sequences involved in sorting proteins to secretory granules have also been observed in otherproteins: prosomatostatin contains an a- helix...