Tài liệu Báo cáo khoa học: "ENHANCING EXPLANATION COHERENCE

Tài liệu Báo cáo khoa học: "ENHANCING EXPLANATION COHERENCE WITH RHETORICAL STRATEGIES MARKT. MAYBURY" pot

... ENHANCING EXPLANATION COHERENCE WITH RHETORICAL STRATEGIES MARK T. MAYBURY Rome Air Development Center Intelligent Interface ... knowledge to enhance the perspicuity of the explanation. - 169 - EXPLANATION RHETORIC The implemented system, EXPLAN, exploits models of rhetorical strategies, focus models, as well as entity-distinguishing ... These sub -strategies, which p...

Ngày tải lên : 22/02/2014, 10:20

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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf

... hematopoietic stem ⁄ precursor cells, trans- duced with only the AF4–MLL transgene, developed an acute lymphoblastic leukemia within  6 months [36]. P-TEFb as potential drug target As outlined above, ... destruction of SMAD3, and thus interferes with transforming growth factor (TGF)b sig- naling [44]. In line with this, GSK3 has recently been identiﬁed in a complex with DDX3 and cell...

Ngày tải lên : 16/02/2014, 14:20

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Tài liệu Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities doc

... allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities is very challenging. We used an in vitro-selected pistol-like (PL) DNAzyme as a DNA scaffold for designing a DNAzyme with dual catalytic ... As compared with PL DNAzyme, DRc DNA- zyme function seemed to have decreased sensitivity to the reaction temperature. DRc DNAzyme exhibited a broad functional range for temperatu...

Ngày tải lên : 16/02/2014, 15:20

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Tài liệu Báo cáo khoa học: Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-r ppt

... nucleolin, with the binding site located within the C-terminal RGG domain of nucleolin [52]. We preincubated sections of E10 chick embryos with 0.5 mgÆmL )1 lactoferrin. This preincuba- tion with ... 100] were diluted in growth medium and incubated with the cells for 30 min at 4 °C. Cells were then washed three times with cold NaCl ⁄ P i and ﬁxed with 4% paraformaldehyde for 15...

Ngày tải lên : 19/02/2014, 05:20

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Tài liệu Báo cáo khoa học: DNA modiﬁcation with cisplatin affects sequence-speciﬁc DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

... cisplatin DNA treatment correlated with the occurrence of sequence motifs forming stable bifunc- tional adducts with the drug (namely, GG and AG doublets) within the target sites. Binding of ... protein with cer- tain response elements can be controlled by changes in DNA topology inducing formation of non-B DNA structures within the binding sites [11,12]. Interactions of p53 with DNA...

Ngày tải lên : 19/02/2014, 05:20

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Tài liệu Báo cáo khoa học: Computational processing and error reduction strategies for standardized quantitative data in biological networks doc

... Wilmington, MA, USA). Livers were perfused with Hanks buffer supplemented with collagenase II (Biochrom, Berlin, Germany). Experiments were carried out in accordance with the German Animal Welfare Act ... (Biochrom) supplemented with l-glutamine and dexamethasone. Cells were starved for 5 h in Williams’ medium E supplemented with l-glutamine. Each dish was stimulated with 40 n...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khóa học: Point mutations associated with insecticide resistance in the Drosophila cytochrome P450 Cyp6a2 enable DDT metabolism doc

... the RDDT R strain were measured with all recombinant proteins, namely testosterone hydroxylation and DDT metabolism. Testosterone was hydroxylated at the 2b position with little quantitative variation ... 271, 1250–1257 (2004) Ó FEBS 2004 doi:10.1111/j.1432-1033.2004.04025.x relation with xenobiotic metabolism or with metabolism of endogenous compounds [24,25]. Models for CYP51 we...

Ngày tải lên : 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Comparison of the substrate speciﬁcity of two potyvirus proteases doc

... mottling virus (TVMV) are members of the family Potyviridae, a subdivision of the picornavirus super group. About 200 potyviruses have been identiﬁed to date. Potyvirus RNA genomes are about 10 kb in ... proteases. Enzyme residues are shown with capped sticks, and the P4 residue of the substrate is shown with ball and stick representation. Comparison of two potyvirus proteases J. To ¨ zse...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: "Learning to Translate with Multiple Objectives" doc

... weakly pareto-optimal if there is no other hypothesis that improves all the metrics; a hypothesis is pareto- optimal if there is no other hypothesis that improves at least one metric without detriment to other ... A hypothesis h ∗ ∈ L is weakly pareto-optimal iff there is no other hypothesis h ∈ L such that M(h) > M (h ∗ ). Weakly pareto-optimal points are a superset of pareto-optimal poin...

Ngày tải lên : 19/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Tet repressor mutants with altered effector binding and allostery docx

... 4-ddma-atc and rescreened for induction with 0.4 lm atc and without inducer on MacConkey agar plates. We screened 17 600 colonies with mutations in helix a1, 29 840 with mutations in helix a4 and 3900 ... repression. TetR i2 -E15A L17V shows repression to 12.5% with 4-ddma-atc and to 58% with atc, thus showing only ﬁvefold improved repression with 4-ddma-atc over atc. A similar...

Ngày tải lên : 20/02/2014, 01:20

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Tài liệu Báo cáo khoa học: "ENHANCING EXPLANATION COHERENCE WITH RHETORICAL STRATEGIES MARKT MAYBURY" pot