Tài liệu Báo cáo Y học: The solution structure and activation of visual arrestin studied by small-angle X-ray scattering pot
Tài liệu Báo cáo Y học: The solution structure and activation of visual arrestin studied by small-angle X-ray scattering pot
... Biochem. 269) 3809 The solution structure and activation of visual arrestin studied by small-angle X-ray scattering Brian H. Shilton1, J. Hugh McDowell2, W. Clay Smith2 and Paul A. Hargrave2,31Department ... withphosphorylated R*.Keywords: visual arrestin; rhodopsin; G-protein coupledreceptor signalling; small-angle X-ray scattering; solution structure. The first event in the visual cycle is activation of ... of the system requires that the signal transmitted by R* be rapidly attenuated. This is accomplished by a two-step process involving phosphorylation of the C-terminus of R* and binding by arrestin. ...
- 9
- 492
- 0
Tài liệu Báo cáo Y học: The glucose-specific carrier of the Escherichia coli phosphotransferase system Synthesis of selective inhibitors and inactivation studies pptx
... the presence of Glc slightly sensitized EIIGlcfor inactivation by the isothiocyanates 1e and 3d. On the other hand, the rate of inactivation by bromoacetyl-Glc (1a) was 15 times fasterthan by bromoacetic ... wererecently introduced for the preparation of C-6 aldehydederivatives of Glc [15]. The key step is the use of Collinsreagent for the selective oxidation of the primary trimethyl-silyl ether of the ... phosphorylated by phosphoenolpyruvate ina reaction catalysed by enzyme I (EI). EI and HPr togetherwith the carbohydrate transporters (enzymes II, EIIsugar )of diverse specificity and structure...
- 12
- 720
- 0
Tài liệu Báo cáo Y học: The RuvABC resolvasome Quantitative analysis of RuvA and RuvC assembly on junction DNA doc
... involves twokey steps: branch migration, catalysed by the RuvB proteinthat is targeted to the Holliday junction by the structure specific RuvA protein, and resolution, which is catalysed by the RuvC ... highly structure specific in its binding to Holliday junctions. The effect of the charge on the central pin with respect to the specificity of the interaction was further investigated by SPR analysis ... quantified the interaction of the RuvA protein with synthetic Holliday junctions and have shown that the binding of the protein is highly struc-ture-specific, and leads to the formation of a complex...
- 10
- 672
- 0
Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc
... in the present structure, butthey have a different orientation of t he hydroxyl groupwith respect to the X-ray structures. Side chain of Lys136has different orientations in each of the X-ray ... Some of the H-bonds present in the human oxidized X-ray structures are observed also in the solution structure. The H-bonds among ring hydrogens of His43 and backbone carbonyls of Thr39 and the ... 2. The H-bond connecting loop III and loop V,containing b hairpin (HN of Leu38 and CO of Gly93) and the H-bond between HN of Gly93 and CO of Asp90 (loopFig. 7. View of the active channel of...
- 11
- 575
- 0
Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... 2 h and 20 h to determine the substratespecificity of the enzyme. The degradation of the polymer and subsequent oligosaccharide formation was analyzed by HPAEC and MALDI-TOF MS. HPAEC analysis ... HPAEC analysis of the hydrolysis of arabinogalactans by GALA. Three different arabinogalactans were used: potato (r), onion (j)andsoy(m). The release of monomers (A), dimers (B), trimers (C) and tetramers ... duplicate. The hydrolysis activity of GALA with different arabino-galactans was measured in duplicate by HPAEC and MALDI-TOF MS after incubation of 1 mgÆmL)1 of potato, onion and soy arabinogalactan...
- 9
- 669
- 0
Tài liệu Báo cáo Y học: The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168 pdf
... characterization of specific enzymes thatare involved in the biosynthesis of these structures and maylead to the discovery of potential therapeutic targets. Inaddition, the correlation of carbohydrate structure ... regarding the sequences of sugar unitswas obtained by FAB-MS of the methylated core OSderivative. Figure 2 and Table 3 shows a series of A-typeprimary glycosyl oxonium ions, and secondary ions, of defined ... biosynthetic pathways in NCTC11168. The sugar composition of the NCTC 11168 polysaccha-rides was examined in earlier studies by Naess and Hofstad[47]. The authors actually noted the presence of...
- 18
- 718
- 0
Tài liệu Báo cáo Y học: The Ikaros family protein Eos associates with C-terminal-binding protein corepressors pptx
... Aiolos and Helios [6–8], and of Eos and Pegasus [9], revealed the existence of a family of related factors. Ikaros, Aiolos and Helios are all abundantlyexpressed in the haematopoietic system and ... shown in (B) and (C). The prominent bands seen above the bands of interest (arrowheads) cor-respond to the heavy chain of the antibodies used because of incom-plete covalent coupling of the antibodies ... representation of Eos constructs tested againstCtBP in the yeast two-hybrid system. Numbers indicate the aminoacids in the Eos sequence, the filled rectangle indicates the position of the PEDLA motif, and...
- 8
- 334
- 0
Tài liệu Báo cáo Y học: The effects of ring-size analogs of the antimicrobial peptide gramicidin S on phospholipid bilayer model membranes and on the growth of Acholeplasma laidlawii B ppt
... related to the asymmetry of shape and possibility also to the size of the peptide molecule. A crudeestimate of these two parameters, based simply on the structure and conformation of these peptides ... magnitude of their perturbation of phospholipid bilayer membranes and the growth of A. laidlawii, generally agrees well with the results of previous studies of the antimicrobial activity of these [5] and ... the integrity of the lipid bilayer of the inner membraneis the primary mode of antimicrobial action of this peptide[8]. In support of this hypothesis, GS has been found tointeract strongly...
- 10
- 683
- 0
Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... very similar type of structure, possibly b ased on the PPII conformation, and which may b eenvisaged as a more open version of the X -ray crystal structure of the Bowman±Birk inhibitor. The ... implying that they behave likesynthetic high polymers in dilute aqueous solution for which the r andom coil model was originally developed. The random coil state is envisaged as the collection of ... using DSC, and aresometimes accessible through X-ray crystallography.It has already been suggested b y Holt & Sawyer [3] that the open and relatively mobile con formation of the c aseins,which...
- 9
- 667
- 0
Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
... methods. Enzyme activity was a nalysed by the standardassay and the i mmunoreactivity was detected by Western blot analysis and quantitated as described i n Materials and methods. Open and filled ... located in the insert within the catalyticdomain, close to the catalytic His264, and the proximity to the active site may explain the effect of oligomerization onenzyme activity. Even though the exact ... that the enzyme was not folded correctly and therefore more easily subjected to proteolysis.Part of the subtilisin-like catalytic N-terminal part of TPP II has been modeled on the structure of...
- 6
- 520
- 0
Từ khóa: tài liệu báo cáo nghiên cứu khoa họcbáo cáo y họctài liệu báo cáotài liệu báo cáo môn triếttài liệu báo cáo tài chínhtài liệu di truyền y họcBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018chuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíChuong 2 nhận dạng rui roGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ