Tài liệu Báo cáo khoa học: "Harnessing NLP Techniques in the Processes of Multilingual Content Management" pptx

... “processing” phase. The language processing tools are integrated in a language processing chain (LPC), so that the output of a given NLP tool is used as an input for the next tool in the chain. The ... solution for multilingual content management addressing the issues posed by the growing family of languages spoken within the EU. We are going to demonstrate the open-source content management ... Firstly, the text is extracted from the input source (text or binary documents) in the “pre-processing” phase. Secondly, the text is annotated by several NLP tools, chained in a sequence in the...

Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx

... integrin-dependentcell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensing of glutamine-induced hepatocyte swelling by integrinsfeeds into ... hepatocyte swelling [12,13], insu-lin-induced hepatocyte swelling is registrated by the integrin system, leading to a Src-dependent activation of the p38-type MAPK and thereby inhibition of autophagic ... outcome.This minireview summarizes recent progress in the understanding of howosmosensing and osmosignaling integrate into the overall context of growthfactor signaling and the execution of apoptotic...

Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf

... the densities correspond to the N- andC-terminal helices of the c ring, respectively. The C-terminal helices show a clear handedness, and two of the rings face in the opposite direction in the membrane ... to the other two, forming the same patternas in the AFM surface representation of Fig. 2A. Bycomparison with the 3D structure of the I. tartaricusc ring [24], the black rings represent the ... view from the cytoplasm (open rings in AFM) and the red ones the view from the extracellular side (smaller, closedrings in Fig. 3). The inner and outer diameters of the rings, measured at the density...

Tài liệu Báo cáo khoa học: "Some Pragmatic Issues in the Planning of Definite and Indefinite Noun Phrases" potx

... capable of distinguishing him from the other guests at the party, not to know who it really is wearing the disguise. Identification of the denotation of a term D is therefore defined as finding ... mutually know of a plan that will result in identification of the intended referent, and in the case of the S[ action, the plan is simply to do nothing, because the referent of the term is already ... scription. In such a situation, the speaker ran augment the description with additional descriptors for tile purpose of informing the hearer that they are true ,ff the denotation of the other...

Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc

... containing atRE in the presence of 1mM bipyridine (B) and liposomes containing atRE, in the presence of 1 mM bipyridine and 6 mM FeSO4(C). The generated retinoidswere analyzed by HPLC. The ... contribute toproviding chromophore to melanopsin to maintaintheir light sensitivities. The expression and function of RPE65c in other cell types in the retina remains to beinvestigated.Earlier ... RPE65c in the inner retina,including Mu¨ller cells, but not in the RPE. Furthermore, double-immuno-staining of dissociated retinal cells using antibodies for RPE65c and gluta-mine synthetase (a...

Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf

... reaction of the luciferin ⁄ luciferase mixture, energydonor (ATP) and oxygen results in the emission of light. The intensity of the bioluminescence was detected using aluminometer, and the mitochondrial ... 2007)doi:10.1111/j.1742-4658.2007.06051.x The mechanisms underlying increased cardioprotection in younger femalemice are unclear. We hypothesized that serine-threonine protein kinase(protein kinase B; Akt) triggers ... insights into thisinteresting question.Conclusions In summary, we have identiﬁed a novel metabolicgene switch (decrease in fatty acid utilization,increase in glucose utilization) in the murine...

Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modiﬁcations ppt

... ligand is involved in the initial homing of leuko-cytes to sites of in ammation [73,74]. The binding of PSGL-1 to P-selectin is largely due to two PTMs,namely an O-glycan that contains tetrasaccharidesialyl-LewisX, ... complete conversion in a matter of hours.As a demonstration of the biological relevance, thismethodology was used to model the P-selectin-bindingdomain of the mucin-like glycoprotein PSGL-1 [73,74].This ... (lacZ)reporter protein. In all cases, the proteins maintainednative function as well as being endowed withadditional lectin-binding properties. The two methods of modiﬁcation, although employing different...

Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx

... conclusion, the identiﬁcation of new metabolites of vitamin D3 made by the action of P450scc willenable us to proceed with further biological testing of these compounds and the investigation of whether ... monohydroxyvi-tamin D3.Because cyclodextrin provides an artiﬁcial means of holding vitamin D3 in solution, we also examined the metabolism of vitamin D3 incorporated into the membrane of phospholipid ... determining the substrates from which they arose by the action of P450scc, as well as the products that they gave rise to.This revealed both the major and minor pathways for the metabolism of vitamin...

Tài liệu Báo cáo khoa học: Bone morphogenetic proteins in the early development of zebraﬁsh pptx

... Follistatin, Chordin and Noggin[12]. These proteins are antagonists of BMP and othermembers of the TGF-b family, binding to and inhibit-ing these signaling molecules from binding to theirreceptors ... theirreceptors in the extracellular space, thus inhibiting ven-tralizing activities. Of these proteins, Chordin has along-range effect. In Xenopus, expression of the chordingene is localized to the dorsal ... rate of Chordin, which may change the preference of site utilization; and (c) promotion of the dissociation of Chordin cysteine-rich (CR)-containingfragments from the ligand. They suggest that the...

Tài liệu Báo cáo khoa học: Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae docx

... most of the proteincomponents are integral in the membrane, most of these mitochondrial pro-teins behave as if they have a-helical transmembrane domains, rather thanb-barrels. These proteins ... protected in the intermembrane space(Fig. 3C). An antibody recognizing the GFP tag at the C-terminus of Om14-GFP shows the electrophoreticmobility of the fusion protein is reduced, indicating a2 ... material (P). Proteins were then analyzed by immunoblotting afterSDS ⁄ PAGE using antisera against the matrix-located mtHsp70, the membrane protein porin and GFP.Integral proteins in the mitochondrial...

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