... Proceedings of the EACL 2009 Demonstrations Session, pages 33–36,
Athens, Greece, 3 April 2009.
c
2009 Association for Computational Linguistics
The Software Architecture for the
First Challenge on ... used online
during EACL at www.give -challenge. org.
In Section 2, we give an introduction to the GIVE
evaluation methodology by describing the experi-
ence of a user...
... spectrum
(Fig. 6B), all the expected correlations from 3-CH in the
A-ring are the same as in the parent vitamin D3. This
further confirms that no hydroxylation occurs in the
A-ring. The new hydroxylated ... by sonication for 10 min in a bath-type
sonicator [22]. Vitamin D3, cholesterol and hydroxyvitamin
D3 derivatives were included in the mixture for sonication as...
...
should be involved in the procedure for their ex-
traction. We incorporate context information in the
form of weights constructed in a fully automatic way.
2.1 The Linguistic Part
The corpus ...
f(a)
the frequency of a in the corpus,
Ta the set of candidate terms that contain a,
P(T~)
the number of these candidate terms.
At this point the incorporation of...
... (2002)
combined an information gain-like metric and the
perplexity reduction criterion for lexicon word se-
lection. The application is on Chinese pinyin-to-
character conversion, which has very ... such information.
With the baseline lexicon, we performed the EM
algorithm as in Table 2 to train the trigram LM.
Here we used a 313 MB LM training corpus, which
contains text news...
... Bax and Bad bind 14-3-3,
the phosphoserine ⁄ threonine binding proteins in the
cytosol. 14-3-3 prevents Bax and Bad dissociation from
translocating to the mitochondria by a conformation
change, ... by containing a
Ser139 phosphorylation site in the C-terminal tail.
Phosphorylation of H2AX on Ser139 is a key event in
the repair of DNA damage and the induction of DNA
degrada...
... to the absorption or release of protons
by the protein or the ligand. If this is the case, the bind-
ing enthalpy is dependent on the ionization enthalpy of
the buffer in which the reaction takes ... An
exception would be the NapD chaperone having a fer-
redoxin-type fold, which undergoes only minor confor-
mational changes upon binding the twin-arginine signal
peptide...
... observed was in the con-
text of the GBD fusion proteins, which contain an
nuclear localization signal within the GBD part of the
protein. Another possible explanation for the observed
autoinhibitory ... a-helix within the HD
that is the primary DNA-binding region, although
there are other DNA contacts outside helix 3 [4–7]. In
addition to binding DNA, the HD is a protei...
... cleft
(Fig. 2). These additional features hinder binding along
the whole interdomain interface, although they both
are displaced upon binding of the ligand.
The N-terminal trunk and the first binding loop
occlude ... compete
with the occluding loop for binding to the active site,
the farther away the occluding loop residues are
shifted. As seen in the tetragonal form of...
... grey) and the C-ter-
minal activation of hMS (grid-barrel) interact with the cobalamin-binding domain. For more information on hMS conformational substates,
see [5] and [33].
K. R. Wolthers and ... S2). The surface corresponding to
the binding region for hMS AD is considerably less
negatively charged in MSR than in the corresponding
region of CPR. The electrostatic surfa...
... their acyl chains,
as the protein itself tilts. Another contribution to the
disordering effect is the restriction of motion along
the acyl chains once the lipids have packed around
the protein. ... examine the effects of increased ionic strength
on the peptide–membrane systems. Even in our longer
100 ns simulations, the positioning and orientation of
melittin at the en...