Tài liệu Báo cáo khoa học: "DESCRIPTION STRATEGIES FOR NAIVE

Tài liệu Báo cáo khoa học: "DESCRIPTION STRATEGIES FOR NAIVE AND EXPERT USERS" pot

... descriptions for the novice tend to include more detail about functional reformation than descriptions for the expert. We have shown how formalization of the strategies allows for the development ... goal is to characterize some of the strategies employed to describe complex physical objects and see whether these strategles are different for naive and experts users...

Ngày tải lên : 21/02/2014, 20:20

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Tài liệu Báo cáo khoa học: "Resumption strategies for an in-vehicle dialogue system" ppt

... questions and the navigation instructions and therefore is the one that is forcing both the inter- view and the navigation task through. 4.3 Workload level The in-vehicle environment is forcing ... means that the most common rea- son for the speaker to interrupt is to ask for or give information that is crucial for the driving task (as opposed for the other and trafﬁc domains,...

Ngày tải lên : 20/02/2014, 04:20

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Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

... mentioning as they should form a rather rigid and hydrophilic peptide. The abundance of Ser and Thr residues in linkers from animals also provides numerous potential targets for O-linked glycosylation. By ... chain. Modeling and molecular dynamics simulations In order to address the possible conformations and motions of the linkers, model building and molecular dynamics simulation...

Ngày tải lên : 14/02/2014, 18:20

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Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx

... experimental condition were built and then compared; spots were quanti- ﬁed on the basis of their relative volume (spot volume nor- malized to the sum of the volumes of all the representative spots) and those that ... putative kinase 1 mutations. Mitochondrial and proteasome dysfunction and oxidative stress could account for the selective degeneration of dopaminergic SNpc neurons a...

Ngày tải lên : 15/02/2014, 01:20

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Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt

... high sensitivity and accuracy, the lectin microarray system is the best tool for a ‘cell proﬁler’, and it is expected to be applicable for selection of cancer-speciﬁc lectins and for quality control ... in serum, and are primary candidates for further validation. Glycoproteins found in the pale gray area are secondary candidates that are thought to be less abundant in serum a...

Ngày tải lên : 16/02/2014, 08:20

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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface pdf

... progression and tumour angiogenesis. Nat Rev Cancer 8, 632–645. 47 Klagsbrun M & Eichmann A (2005) A role for axon guidance receptors and ligands in blood vessel development and tumor angiogenesis. ... diffusion of oxygen and nutri- ents is no longer adequate for survival [14] and a hyp- oxic gradient forms inside the body to signal for the formation of new vessels. In...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor doc

... cells and astrocytes, and the tight junctions of vascular endothelial cells (ECs) in the BBB are well organized with claudins and ZO- proteins through a decrease in angiogenesis signaling and an ... in both embryogenesis and adulthood, and functions by binding with two tyrosine kinase receptors, VEGFR-1 (Flt-1) and VEGFR-2 (KDR ⁄ Flk-1), Fig. 1. The VEGF–VEGFR system and the...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke docx

... angiogenesis and neurogenesis responses in the delayed stroke phase. VEGF can trigger remod- eling responses in both endothelial cells and neurons (see Fagan et al. [57] and Hansen et al. [58] for full and ... substrates required for later angiogenesis and brain recovery (Fig. 3). Because similar signals and substrates are involved, one will have to be very careful in terms of...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx

... as a risk factor for PD [13,14] and for Lewy body disorders [15]. Neurodegeneration with brain iron accumulation-1 (NBIA-1), formerly known as Hallervorden–Spatz disease is a form of neurodegeneration ... appear normal for 1 or 2 years with symptoms appearing between 2 and 4 years. They gradually develop neurologic abnormali- ties which are initially manifested by ataxia, grand mal...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc

... of Vrp1p and Las17p in yeast and WIP and WASP-fam- ily proteins in mammalian cells are direct and result in constitutive and apparently stable complexes [28,29,31,32]. In yeast, Vrp1p and Las17p ... yeast lysates and directly binds puriﬁed yeast and rabbit skeletal muscle G-actin in vitro (Fig. 4B–D and data not shown). Mutations of K485 and R486 abolish both two-hybrid in...

Ngày tải lên : 18/02/2014, 16:20

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