... 269) Ó FEBS 2002 Functional analysis of a small heat shock/a-crystallin protein from Artemia franciscanaOligomerization and thermotoleranceJulie A. Crack, Marc Mansour, Yu Sun and Thomas H. MacRaeDepartment ... ordinary hydration andtemperature, cell maintenance entails a constant andsubstantial free energy flow [51,52]. Anoxic cysts m ayacquire s ufficient energy to survive b y utilization of guanosine ... example of stress resistance, fully hydrated cystssurvive several years at physiological temperature in thecomplete absence o f o xygen [48,51,52,54], an unusual degree of tolerance for any animal....