... (VP16- MT1 Y, VP16 -MT1 LL, VP16 -MT1 FRR, VP16 -MT1 HGT, VP16 -MT1 PRR, VP16 -MT1 LLY, VP16 -MT1 CQR, VP16 -MT1 SLL, VP16 -MT1 DKV), MT2 -MMP(VP16 -MT2 LLY), MT3 -MMP (VP16 -MT3 ILY) and MT5 -MMP (VP16 -MT5 ... GRASP55 MT5 VP16+GAL4 GRASP55 MT5 VTYVP16789 MT2 MT3 MT2 MT2 LLYFig. 6. The MT2 -MMP LLY motif is involvedin the interaction with GRASP55. (A)Schematic representation of the VP16 -MT1 ,VP16 -MT2 , ... interaction with MT1 -MMP.GRASP55 interacts with MT2 -, MT3 - and MT5 -MMP The sequences of cytoplasmic domains of the four MT- MMPs are conserved (Fig. 6A). Interestingly, the LLY573motif in MT1 -MMP...