... astrocyticCa2+transients are accentuated in pathological con-ditions, suggesting the involvement of astrocytic Ca2+transients in brain disorders, including epileptic sei-zures. Interestingly, astrocytes also ... pathological conditions, suggesting that, in addi-tion to physiological events, they might be closely involved in disorders in the central nervous system.Abbreviations[Ca2+]i, intracellular Ca2+concentration; ... signaling between astro-cytes and neurons could be involved in the regulationof synaptic transmission both in physiological and in pathophysiological conditions. In this minireview, the mechanisms...