Tài liệu Báo cáo khoa học: "Multi-Modal Annotation of Quest Games in Second Life" pdf

Tài liệu Báo cáo khoa học: Improving Classification of Medical Assertions in Clinical Notes" pdf

... the training data to measure the impact of each of the four subsets of features explained in Section 3. Ta-ble 3 shows the cross validation results when cu-mulatively adding each set of features. ... Syntactic Features: Part -of- speech tags of the three words preceding the medical term and the three words following it. 312create one classifier for each type of label using instances with that ... by manually examining the training data: Lexical Features: The medical term itself, the three words preceding it, and the three words fol-lowing it. We used the LVG annotator in Lexical Tools...

Tài liệu Báo cáo khoa học: "Multi-Modal Annotation of Quest Games in Second Life" pdf

... activities (quest- ing, competing, fighting, etc.) and communicate via chat or speech using assumed screen names. We collected a corpus of 48 group quests in Second Life that jointly involved ... current DA tagging as a work in progress. 4.3.3 Zone coding Each of the five main areas had a correspond-ing set of subzones. A subzone is a building, a room within a building, or any other ... corresponding se-ries of progressive moments in time portraying en-try into the Bank subzone as represented in RAT. In the annotation, each avatar name is recorded in or-der of its entry into the subzone...

Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf

... earlier, oxidation of pyruvate in the E1 com-ponent of PDHc is coupled to reductive acetylation of lipoic acid covalently attached in amide linkage to thee-amino function of a lysine in the E2 component. ... additional E3 bindingprotein and speciﬁc kinases and phosphatases, whichcontrol the activity of the complex by reversible phos-phorylation ⁄ dephosphorylation of serine side chains in E1 [4]. Initially, ... ferredoxinis suspected to bind. Electron tunneling is likely toproceed dominantly in a through-bond mechanisminvolving the backbone and coordinating cysteinylligands of the iron-sulfur clusters....

Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt

... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati,OH, USA) constantly maintained at 1% O2. Culturemedium ... cultured in DMEM containing 10% fetal bovineserum. OP9 cells were grown in aMEM containing 20%fetal bovine serum. C2C12 cells were maintained in DMEMcontaining 10% fetal bovine serum.Adipogenic ... serumand IDM (10 lgÆmL)1insulin, 1 lm dexamethasone, and0.5 mm IDM). Cells were then maintained in DMEM con-taining 10% fetal bovine serum and 1 lgÆmL)1insulin. Themedium was replaced...

Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf

... interact with a number of functionalgroups, including the aromatic side chains of someamino acids, through a stacking mechanism [42]. Theinteraction of arginine with aromatic amino acids of aB-crystallin ... that aB-crystallin most likelyemploys various methods of binding (or bindingmodes) in order to prevent the aggregation of stressedproteins. Some of these binding modes (or bindingsites) are ... of insulin.ACBFig. 2. aB-crystallin protects against theDTT-induced aggregation of insulin, and thisactivity is enhanced by Arg-HCl. Insulin(, 0.25 mgÆmL)1) was incubated at 37 °Cin...

Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx

... detected atthe dimer interface of the models or in the surroundings of the hinge loop residues. Likewise, the models of nonex-changing and exchanging HHP-RNase were prepared start-ing from 1Z7X. ... strong, neutralizing action of the cytosolic RNaseinhibitor (cRI), a 50-kDa protein containing 16 leu-cine-rich repeat motifs [7,8]. In fact, onconase fromRana pipiens eggs [9], and seminal RNase ... detected at the dimerinterface of the models or in the surroundings of themutated residues. The models of RNase A covalent dimers in the exchanging conformation were prepared using the7RSA structure...

Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf

... extension to the protein kinase folds backon the kinase domain and interferes with the substratebinding sites. In the case of the titin and twitchinkinases, the autoinhibitory sequence acts ... hexadecameric enzyme consisting of four copies of four subunits: (abcd)4. An intrinsic calmodulin (CaM, the dsubunit) binds directly to the c protein kinase chain. The interaction site of CaM on c has ... PhKcsubunit encodes a C-terminal extension to the proteinkinase domain and treatment of the kinase withKeywordscalmodulin; kinase regulation; protein–protein interaction; NMR spectroscopyCorrespondenceJ....

Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafﬁcking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efﬁcient GABA-uptake activity of the GABA transporter pptx

... substratebinding process. This provides strong evidence thatN-glycans, in particular their terminal structures, areinvolved in regulating the GABA translocation of GAT1, but not in binding of GAT1 ... not the terminaltrimming of N-glycans is involved in the regulation of the stability and trafﬁcking of GAT1. It has beenreported that a variety of molecular chaperones andfolding enzymes assist ... folding of newly synthesizedproteins in the ER. If N-glycosylation is inhibited,some glycoproteins fail to fold or assemble efﬁciently,resulting in a prolonged retention in the ER and anincreased...

Tài liệu Báo cáo khoa học: "Topological Ordering of Function Words in Hierarchical Phrase-based Translation" pdf

... Y)326NN = 2048N = 128N = 64N = 2048331Proceedings of the 47th Annual Meeting of the ACL and the 4th IJCNLP of the AFNLP, pages 324–332,Suntec, Singapore, 2-7 August 2009.c2009 ACL and AFNLP1...

Tài liệu Báo cáo khoa học: "Automatic Evaluation of Sentence-Level Fluency Andrew Mutton∗" pdf

... Re-evaluating the Role of Bleu in Machine TranslationResearch. In Proceedings of EACL, pages 249–256.Jos´e Coch. 1996. Evaluating and comparing three text-production strategies. In Proceedings of ... disappoint-ing, given an expectation that introducing structurewould make sentences more natural and hence leadto a range of sentence qualities. In hindsight, thisis not so surprising; in generating ... wereinterested in the level of agreement of intuitive un-derstanding of ﬂuency. We instructed them also thatthey should evaluate the sentence without consider-ing its content, using Colourless...

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