Tài liệu Báo cáo khoa học: Peroxiredoxin II functions as a s

Tài liệu Báo cáo khoa học: Peroxiredoxin II functions as a signal terminator for H2O2-activated phospholipase D1 doc

... Peroxiredoxin II functions as a signal terminator for H 2 O 2 -activated phospholipase D1 Nianzhou Xiao, Guangwei Du and Michael A. Frohman Department of Pharmacology and the Center for Developmental ... and PMA-stimu- lated CHO cells (63 ·). Rabbit antibody to PrxII and an Alexa-647-labeled goat anti- rabbit IgG secondary were used to visualize PrxII. Mouse monoclonal...

Ngày tải lên : 20/02/2014, 01:20

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Tài liệu Báo cáo khoa học: Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain doc

... RNA for RNAase protection assay. M indicates the 124-base pair marker transcript (M), the full-length probe is indicated by a line, and the protected fragment is indicated by an arrow. The RNAase ... RNA subjected to protection assay. The ﬁlm exposure was for 5 days. (C) Heart, kidney, lung and spleen RNA from each of three animals was analysed for Cyp4x1 RNA, and a 5-day exposure o...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Computational approaches to understand a-conotoxin interactions at neuronal nicotinic receptors doc

... 2329 Exploration at the molecular level of models of the neuronal nAChRs As neuronal nAChRs are attractive targets for treating many diseases such as cognitive dysfunction, neurodegeneration and other ... powerful computational tools available today is facilitating drug design at the nAChRs. Acknowledgements We thank Joel Tyndall, Christina Schroeder and Ivana Saska for their comments...

Ngày tải lên : 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: "An Affect-Enriched Dialogue Act Classification Model for Task-Oriented Dialogue" doc

... dialogue act. 5.3 Classification Results The classification accuracy and kappa for each specialized classifier is displayed in Table 4. Note that kappa statistics adjust for the accuracy that would ... and adjacent subtasks are semantically more similar than subtasks at a greater distance); therefore, a weighted kappa is also meaningful to consider for this annotation. The...

Ngày tải lên : 20/02/2014, 04:20

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Tài liệu Báo cáo khoa học: C-Terminal extension of a plant cysteine protease modulates proteolytic activity through a partial inhibitory mechanism doc

... ex 114 aa 208 aa 24 aa BamH 34 aa Start Stop Xho1 N -Pro Protease domain Protease domain CT - ex 380 aa 1 II NP 114 aa 208 aa BamH1 34 aa Start Stop Xho1 SS SS G SSS S N-Pro 356 aa III MSTLFII S ILLFLAS F SYAMDI S TIEYKYDKSS AWRTDEEVKEIYELWLAKHDKVY SG LVEYEKRFEIFKDNLKFIDEH NSENHTYKMGLTPYTDLTNEEFQAIYLGTRSDTIHRLKRTINISERYAYEAGDNLPEQIDWRKKGAVTPVKNQGKCG SCWAFSTVSTVESINQIRTGNLISLSEQQLVDCNKKNHG C...

Ngày tải lên : 14/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt

... importin -a nuclear import pathway, provided that CLIC4 can undergo a conforma- tional rearrangement that exposes the NLS in an extended conformation. Database Structural data are available in ... atoms) and r j is the standard deviation of B factors. The normalized B factors have a zero mean and unit variance. All atoms that satisfy B z ‡ 4 are treated as outliers and discarded. After...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Kinetics of dextran-independent a-(1 ﬁ 3)-glucan synthesis by Streptococcus sobrinus glucosyltransferase I pdf

... Methyl a- d-glucopyranoside was used as a glucose analog that is not a substrate of hexokinase in a glucose assay system. The data were analyzed on the basis of the Michaelis–Menten equation; the maximum activity ... weights of activated carbon (Wako Pure Chemical, Osaka, Japan) and Celite (Wako Pure Chemical) (Fig. S4). The column was maintained at 15 °C, and was then washed with wa...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a coupled oscillator-based mechanism in smooth muscle ppt

... Pharmacology, University of Calgary, Alberta, Canada 2 School of Biomedical Sciences, University of Newcastle, Callaghan, NSW, Australia Long-range signaling Biological organs display coordinated ... membrane depolarization activating or advancing the phase of other Ca 2+ stores. The electrical and chemical transduction pathways are as depicted in Fig. 3. The key mechanisms are as follows...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a capacitative (AC) electrical coupling model in neuroepithelium pptx

... MINIREVIEW Synchronization of Ca 2+ oscillations: a capacitative (AC) electrical coupling model in neuroepithelium Masayuki Yamashita Department of Physiology I, Nara Medical University, Kashihara, Japan Structural ... packed in the basal layer (Fig. 1C). The voltage ﬂuctuations of the Ca 2+ store will induce ACs, which can pass the series capaci- tance of the ONM and the plasma membrane a...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping ppt

... malachite green GTPase assay. The fraction at 33 mL contained no detectable protein and was assayed as an internal control to establish that incubation with the column buffers alone did not facil- itate ... glycerol and TMAO and the benzyl viologen-linked TMAO reductase activity of periplasmic fractions was assayed (Fig. 7A) . TorD D68W was observed to support assembly of the periplasmic TM...

Ngày tải lên : 16/02/2014, 09:20

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