... MT1-MMPactivation of MMP-2, can also take part in the secondautoactivation step and function as an activator bypromoting conversion of the 64 kDa intermediate to the fully active 62 kDa form. ... Further, autoactivation of the active 62 kDa form to a C-terminally truncated45 kDa form was also inhibited by TIMP-1.Investigation of mechanisms that may explain the increased activation of ... J, Takahashi R, Kondo S, Mizoguchi A, Adachi E,Sasahara RM, Nishimura S, Imamura Y, Kitayama H,Alexander DB et al. (2001) The membrane-anchoredMMP inhibitor RECK is a key regulator of extracellu-lar...